Evidence map›Paper›PMID 34354969›Full record

ArticleFrontiers in pediatrics2021

The First Case Report of X-Linked Sideroblastic Anemia With Ataxia of Chinese Origin and Literature Review.

Shiqiu Xiong, Yang Jia, Shijun Li, Peng Huang, Jie Xiong, Dingan Mao, Qingnan He, Liqun Liu

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Strabismus in Genetic Syndromes: A Review.Clinical & experimental ophthalmology · 2025
    Review
  2. Pulling back the mitochondria's iron curtain.npj metabolic health and disease · 2025
    Review
  3. Review
  4. Review
  5. A novel and apparentFrontiers in pediatrics · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Shiqiu XiongDepartment of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, China.
Yang JiaDepartment of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, China.
Shijun LiDepartment of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, China.
Peng HuangDepartment of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, China.
Jie XiongDepartment of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, China.
Dingan MaoDepartment of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, China.
Qingnan HeDepartment of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, China.
Liqun LiuDepartment of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, China.
Central South University · CNSecond Xiangya Hospital of Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

X-linked sideroblastic anemia with ataxia (XLSA/A) is a rare X-liked inherited disease, which was linked to the ABCB7 gene mutations. So far, five families have been reported worldwide. We present the first Chinese family of XLSA/A with novel ABCB7 gene mutation (c.2024A > G) and make a retrospective literature review. All affected patients were male. Age of symptom onset was <2 years old. The main symptoms included ataxia, delay in motor development, and mild sideroblastic anemia with obviously increased erythrocyte protoporphyrin. In this case, he had new symptoms that had not been reported in other cases such as epilepsy and cryptorchidism. We also discuss the possible molecular mechanism linking ABCB7 gene mutations to sideroblastic anemia and ataxia.

Indexed as

ABCB7 geneataxiasideroblastic anemiaX-linked sideroblastic anemia with ataxiaXLSA/A

Identifiers

PMID34354969
PMCPMC8329551
OpenAlexW3184598859

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.