Evidence map›Paper›PMID 34354949›Full record

ArticleFrontiers in oncology2021

Virtual Patient-Specific Quality Assurance of IMRT Using UNet++: Classification, Gamma Passing Rates Prediction, and Dose Difference Prediction.

Ying Huang, Yifei Pi, Kui Ma, Xiaojuan Miao, Sichao Fu, Hua Chen, Hao Wang, Hengle Gu, Yan Shao, Yanhua Duan and 5 more

Abstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ying HuangShanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.
Yifei PiDepartment of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Kui MaVarian Medical Systems (China), Beijing, China.
Xiaojuan MiaoDepartment of Hematology, Western Theater General Hospital, Chengdu, China.
Sichao FuDepartment of Hematology, Western Theater General Hospital, Chengdu, China.
Hua ChenShanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.
Hao WangShanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.
Hengle GuShanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.
Yan ShaoShanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.
Yanhua DuanShanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.
Aihui FengShanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.
Jiyong WangPingAn Health Technology Co. Ltd, Shanghai, China.
Ruxin CaiShanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.
Weihai ZhuoKey Laboratory of Nuclear Physics and Ion Beam Application Ministry of Education, Fudan University, Shanghai, China.
Zhiyong XuShanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dose verification in radiotherapy quality assurance (QA) is time-consuming and places a heavy workload on medical physicists. To provide a clinical tool to perform patient specific QA accurately, the UNet++ is investigated to classify failed or pass fields (the GPR lower than 85% is considered "failed" while the GPR higher than 85% is considered "pass"), predict gamma passing rates (GPR) for different gamma criteria, and predict dose difference from virtual patient-specific quality assurance in radiotherapy. UNet++ was trained and validated with 473 fields and tested with 95 fields. All plans used Portal Dosimetry for dose verification pre-treatment. Planar dose distribution of each field was used as the input for UNet++, with QA classification results, gamma passing rates of different gamma criteria, and dose difference were used as the output. In the test set, the accuracy of the classification model was 95.79%. The mean absolute error (MAE) were 0.82, 0.88, 2.11, 2.52, and the root mean squared error (RMSE) were 1.38, 1.57, 3.33, 3.72 for 3%/3mm, 3%/2 mm, 2%/3 mm, 2%/2 mm, respectively. The trend and position of the predicted dose difference were consistent with the measured dose difference. In conclusion, the Virtual QA based on UNet++ can be used to classify the field passed or not, predict gamma pass rate for different gamma criteria, and predict dose difference. The results show that UNet++ based Virtual QA is promising in quality assurance for radiotherapy.

Indexed as

deep learningdose differenceprediction modelquality assuranceradiotherapy

Identifiers

PMID34354949
PMCPMC8330420

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.