Evidence map›Paper›PMID 34354927›Full record

ArticleMolecular genetics and metabolism reports2021

Protective effects of alpha-lipoic acid on hair cell damage in diabetic zebrafish model.

Eunmi Kim, Dong-Won Lee, Hae-Chul Park, Dong Hwee Kim

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular genetics and metabolism reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Comparing the effects of developmental exposure to alpha lipoic acid (ALA) and perfluorooctanesulfonic acid (PFOS) in zebrafish (Danio rerio).Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2024
    Article
  2. Article
  3. Diabetes mellitus and hearing loss.Molecular medicine (Cambridge, Mass.) · 2023
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Eunmi KimDepartment of Biomedical Sciences, College of Medicine, Korea University, Ansan 15355, Republic of Korea.
Dong-Won LeeDepartment of Biomedical Sciences, College of Medicine, Korea University, Ansan 15355, Republic of Korea.
Hae-Chul ParkDepartment of Biomedical Sciences, College of Medicine, Korea University, Ansan 15355, Republic of Korea.
Dong Hwee KimDepartment of Physical Medicine and Rehabilitation, College of Medicine, Korea University, Ansan 15355, Republic of Korea.
Korea University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hearing impairment is one of the complications in diabetes mellitus; however, there are very few therapeutic studies on it. In this study, we investigated the protective effect of alpha-lipoic acid (ALA) on hearing loss in diabetic transgenic zebrafish and confirmed that ALA protects the loss of hair cells (HCs) caused by hyperglycemia. The data indicated that ALA has a protective effect on the damage to HCs in diabetic zebrafish.

Indexed as

ALA, alpha-lipoic acidAlpha-lipoic acidDiabetes mellitusDM, diabetes mellitusEM, embryo mediumHair cellHCs, hair cellsPancreatic β-cellZebrafish

Identifiers

PMID34354927
PMCPMC8322127
OpenAlexW3187274917

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.