Evidence map›Paper›PMID 34354857›Full record

ArticleAmerican journal of cancer research2021

Epimedokoreanin C, a prenylated flavonoid isolated from

Xiaoqing Liu, Shuqi Wang, Hao Zheng, Qingying Liu, Tao Shen, Xiaoning Wang, Dongmei Ren

Open access · greenAbstract read
In one paragraph

Article in American journal of cancer research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. A comprehensive narrative review ofJournal of pharmaceutical analysis · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Cellular Regulation of Macropinocytosis.International journal of molecular sciences · 2024
    Review
  9. Frontiers in pharmacology · 2024
    Article
  10. Article
  11. Review
  12. Diversity and complexity of cell death: a historical review.Experimental & molecular medicine · 2023
    Review
  13. Article
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xiaoqing LiuKey Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University 44 West Wenhua Road, Jinan 250012, P. R. China.
Shuqi WangKey Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University 44 West Wenhua Road, Jinan 250012, P. R. China.
Hao ZhengKey Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University 44 West Wenhua Road, Jinan 250012, P. R. China.
Qingying LiuKey Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University 44 West Wenhua Road, Jinan 250012, P. R. China.
Tao ShenKey Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University 44 West Wenhua Road, Jinan 250012, P. R. China.
Xiaoning WangKey Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University 44 West Wenhua Road, Jinan 250012, P. R. China.
Dongmei RenKey Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University 44 West Wenhua Road, Jinan 250012, P. R. China.
Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methuosis is a novel type of non-apoptotic cell death characterized by accumulation of cytoplasmic vacuoles. Identification of molecules that induce methuosis may provide alternative therapeutics for cancers that are refractory to apoptosis. Epimedokoreanin C (EKC) is a prenylated flavonoid isolated from a Chinese herb

Indexed as

Arf6epimedokoreanin CmacropinocytosisMethuosisRac1

Identifiers

PMID34354857
PMCPMC8332866
OpenAlexW3113597710

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.