Evidence map›Paper›PMID 34354762›Full record

ArticleBiomedical signal processing and control2020

Longitudinal brain tumor segmentation prediction in MRI using feature and label fusion.

Linmin Pei, Spyridon Bakas, Arastoo Vossough, Syed M S Reza, Christos Davatzikos, Khan M Iftekharuddin

Open access · greenAbstract read
In one paragraph

Article in Biomedical signal processing and control, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 67 citations in OpenAlex.

  1. Review
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  6. Brain tumor segmentation based on the U-NET+⁣+ network with efficientnet encoder.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024
    Article
  7. Highly accurate brain tumor detection with high sensitivity using transform-based functions and machine learning algorithms.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Linmin PeiVision Lab, Electrical & Computer Engineering, Old Dominion University, Norfolk, VA 23529, USA.
Spyridon BakasCenter for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, PA 19104, USA.
Arastoo VossoughDepartment of Radiology, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA 19104, USA.
Syed M S RezaVision Lab, Electrical & Computer Engineering, Old Dominion University, Norfolk, VA 23529, USA.
Christos DavatzikosCenter for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, PA 19104, USA.
Khan M IftekharuddinVision Lab, Electrical & Computer Engineering, Old Dominion University, Norfolk, VA 23529, USA.
Old Dominion University · USUniversity of Pennsylvania · USChildren's Hospital of Philadelphia · US

Funding

Statistical atlases of brain tumor MRI:do imaging phenotypes predict progression?R01NS042645 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS · 2002 to 2024
$8.7M
Quantitative imaging and molecular data modeling for brain tumor recurrence and progression analysisR01EB020683 · NIBIB · OLD DOMINION UNIVERSITY · PI Khan M Iftekharuddin · 2016 to 2026
$3.2M
Cancer imaging phenomics software suite: application to brain and breast cancerU24CA189523 · NCI · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS, KONTOS, DESPINA · 2015 to 2019
$3.2M
Biomedical Image Computing and Informatics ClusterS10OD023495 · OD · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS · 2017 to 2017
$1.9M
NCI NIH HHS U24 CA189523NIBIB NIH HHS R01 EB020683NIH HHS S10 OD023495NINDS NIH HHS R01 NS042645
6 · The paper itself

Abstract

This work proposes a novel framework for brain tumor segmentation prediction in longitudinal multi-modal MRI scans, comprising two methods; feature fusion and joint label fusion (JLF). The first method fuses stochastic multi-resolution texture features with tumor cell density feature to obtain tumor segmentation predictions in follow-up timepoints using data from baseline pre-operative timepoint. The cell density feature is obtained by solving the 3D reaction-diffusion equation for biophysical tumor growth modelling using the Lattice-Boltzmann method. The second method utilizes JLF to combine segmentation labels obtained from (i) the stochastic texture feature-based and Random Forest (RF)-based tumor segmentation method; and (ii) another state-of-the-art tumor growth and segmentation method, known as boosted Glioma Image Segmentation and Registration (GLISTRboost, or GB). We quantitatively evaluate both proposed methods using the Dice Similarity Coefficient (DSC) in longitudinal scans of 9 patients from the public BraTS 2015 multi-institutional dataset. The evaluation results for the feature-based fusion method show improved tumor segmentation prediction for the whole tumor(

Indexed as

BraTSFeature and label fusionLattice-Boltzmann methodLongitudinal MRIReaction-diffusion equationTexture featuresTumor segmentation prediction

Identifiers

PMID34354762
PMCPMC8336640
OpenAlexW2972255961

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.