Evidence map›Paper›PMID 34354753›Full record

ArticleStem cells international2021

Development of a Human Intestinal Organoid Model for

Leonidas Kandilogiannakis, Eirini Filidou, Ioannis Drygiannakis, Gesthimani Tarapatzi, Stylianos Didaskalou, Maria Koffa, Konstantinos Arvanitidis, Giorgos Bamias, Vassilis Valatas, Vasilis Paspaliaris and 1 more

Open access · goldAbstract read
In one paragraph

Article in Stem cells international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

  1. AnBiofabrication · 2025
    Article
  2. Review
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  7. Advancing Synthetic Hydrogels through Nature-Inspired Materials Chemistry.Advanced materials (Deerfield Beach, Fla.) · 2024
    Review
  8. Article
  9. In Vitro Models for Investigating Intestinal Host-Pathogen Interactions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  10. AnFrontiers in immunology · 2024
    Article
  11. Recent Advances in Cell-Based In Vitro Models to Recreate Human Intestinal Inflammation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  12. [Progress on three-dimensional cell culture technology and their application].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Leonidas KandilogiannakisLaboratory of Pharmacology, Faculty of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.ORCID https://orcid.org/0000-0002-5982-4210
Eirini FilidouLaboratory of Pharmacology, Faculty of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.ORCID https://orcid.org/0000-0002-7146-4684
Ioannis DrygiannakisGastroenterology and Hepatology Research Laboratory, Medical School, University of Crete, Heraklion, Greece.ORCID https://orcid.org/0000-0001-5845-2040
Gesthimani TarapatziLaboratory of Pharmacology, Faculty of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.ORCID https://orcid.org/0000-0002-6877-5991
Stylianos DidaskalouLaboratory of Molecular Cell Biology, Department of Molecular Biology and Genetics, Democritus University of Thrace, Alexandroupolis, Greece.ORCID https://orcid.org/0000-0001-5932-9626
Maria KoffaLaboratory of Molecular Cell Biology, Department of Molecular Biology and Genetics, Democritus University of Thrace, Alexandroupolis, Greece.ORCID https://orcid.org/0000-0003-2255-3426
Konstantinos ArvanitidisLaboratory of Pharmacology, Faculty of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.ORCID https://orcid.org/0000-0003-0639-2474
Giorgos BamiasGI-Unit, Third Department of Internal Medicine, National & Kapodistrian University of Athens, Sotiria Hospital, Athens, Greece.ORCID https://orcid.org/0000-0002-5492-5717
Vassilis ValatasLaboratory of Pharmacology, Faculty of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.ORCID https://orcid.org/0000-0001-6660-0621
Vasilis PaspaliarisTithon Biotech Inc., San Diego, USA.ORCID https://orcid.org/0000-0003-0274-3046
George KoliosLaboratory of Pharmacology, Faculty of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.ORCID https://orcid.org/0000-0002-2066-4782
Democritus University of Thrace · GRUniversity of Crete · GRNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory Bowel Diseases (IBDs) are characterized by chronic intestinal inflammation and fibrosis, the latter being the predominant denominator for long-term complications. Epithelial and mesenchymal 2D cultures are highly utilized

Identifiers

PMID34354753
PMCPMC8331310
OpenAlexW3186359460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.