ReviewInternational journal of endocrinology2021
The Accuracy of Visceral Adiposity Index for the Screening of Metabolic Syndrome: A Systematic Review and Meta-Analysis.
Review in International journal of endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- The accuracy of lipid accumulation product to predict metabolic syndrome in PCOS: a meta-analysis and comparative analysis with other indicators.Frontiers in endocrinology · 2026Pooled it
- Association of insulin resistance surrogate indices and erectile dysfunction: a systematic review and meta-analysis.Reproductive biology and endocrinology : RB&E · 2024Pooled it
- Association Between Visceral Obesity Index and Diabetes: A Systematic Review and Meta-analysis.The Journal of clinical endocrinology and metabolism · 2024Pooled it
- Gender-specific accuracy of lipid accumulation product index for the screening of metabolic syndrome in general adults: a meta-analysis and comparative analysis with other adiposity indicators.Lipids in health and disease · 2024Pooled it
- Diagnostic value of visceral adiposity index in chronic kidney disease: a meta-analysis.Acta diabetologica · 2023Pooled it
- Effects of Combined Training on Visceral Adiposity Index and Metabolic Phenotype in Obesity: A Randomized Clinical Trial.International journal of environmental research and public health · 2025Trial
- Association Between Visceral Adiposity Index and Metabolic Syndrome and Its Components: Evidence From the PERSIAN Guilan Cohort Study.Endocrinology, diabetes & metabolism · 2026Article
- Association between visceral adiposity index and delayed union/nonunion after tibial or femoral shaft fractures: a single-center retrospective cohort study.BMC musculoskeletal disorders · 2026Article
- Low-Carbohydrate Diet and Metabolic Syndrome Risk in Korean Adults: A Korea National Health and Nutrition Examination Survey Study.Nutrients · 2026Article
- Comparison of four diagnostic indices for metabolic syndrome in a Northern Spanish population.PloS one · 2026Observational
- Clinical indices and anthropometric measures for magnetic resonance imaging-defined visceral adiposity across the hypercortisolism spectrum.Frontiers in endocrinology · 2026Article
- Exploring inflammation and adipose tissue dysfunction in metabolically healthy versus unhealthy obesity among Arab adults.Diabetology & metabolic syndrome · 2025Article
- Association between visceral adiposity index and hyperuricemia and gout among US adults: a cross-sectional analysis of NHANES 2007-2018.Scientific reports · 2025Article
- Association of novel visceral obesity indices with 10-year risk of major cardiovascular events in patients with type 2 diabetes mellitus.The Journal of the Egyptian Public Health Association · 2025Article
- Visceral adiposity index as a predictor of metabolic dysfunction-associated steatotic liver disease: a cross-sectional study.BMC gastroenterology · 2025Article
- Predictive Capacity of Different Indicators of Adiposity for Metabolic Syndrome in Adults in the City of Trujillo, Peru.Medicina (Kaunas, Lithuania) · 2025Article
- Article
- Predictive Accuracy of Biochemical and Anthropometric Indices for Metabolic Syndrome in Children with Obesity: A Comparative Study.Life (Basel, Switzerland) · 2025Article
- IL-6 as an integrative biomarker of residual inflammation and visceral adiposity in psoriasis: a VAI threshold-dependent model.Frontiers in immunology · 2025Article
- The non-linear relationship between the visceral adiposity index and the risk of prediabetes and diabetes.Frontiers in endocrinology · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsVisceral adiposity index (VAI) is a novel marker of fat distribution and function which incorporates both anthropometric and laboratory measures. Recently, several studies have suggested VAI as a screening tool for metabolic syndrome (MetS). Here, we aimed to consolidate the results of these studies by performing a systematic review and meta-analysis. METHODS AND
resultsWe searched PubMed and EMBASE online databases for eligible studies that investigated the association of VAI and MetS. After reviewing 294 records, we included 33 eligible papers with a sum of 20516 MetS and 53242 healthy participants. The risk of bias in the included studies was assessed, and the relevant data was extracted. All included studies reported a significant association between VAI and MetS screening, but were highly heterogeneous in their reported effects. We pooled the diagnostic test accuracy metrics of VAI for MetS screening and showed that it has a moderate-to-high accuracy with an area under the summary receiver operating characteristics curve of 0.847, a pooled sensitivity of 78%, and a pooled specificity of 79%. Besides, we pooled the difference in means of VAI between patients with MetS and healthy controls, revealing that VAI was 2.15 units higher in MetS patients.
conclusionsVAI is an accurate, low-cost, and widely available screening marker for MetS. However, further studies are needed to evaluate its applicability in clinical practice, determine an optimal cut-off, and identify populations that would benefit the most from it.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.