Evidence map›Paper›PMID 34354552›Full record

ArticleContrast media & molecular imaging2021

Magnetic Resonance Imaging (MRI) Differential Diagnosis of Meningiomas Using ANOVA.

Jinhuan Liu, Jun Chen, Yunfei Zha, Yabin Huang, Feifei Zeng

Open access · hybridAbstract read
In one paragraph

Article in Contrast media & molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jinhuan LiuDepartment of Radiology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.ORCID 0000-0001-6162-7534
Jun ChenDepartment of Radiology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.ORCID 0000-0002-1379-0481
Yunfei ZhaDepartment of Radiology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.ORCID 0000-0002-2386-5221
Yabin HuangDepartment of Pathology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.ORCID 0000-0002-7811-9912
Feifei ZengDepartment of Radiology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.ORCID 0000-0002-6600-1888
Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work explored the diagnostic value of different subtypes of meningiomas under T2WI low signal based on analysis of variance (ANOVA), and the expression differences of Ki67, VEGF, and P73 in different subtypes were analyzed. 67 patients with meningioma confirmed surgically and pathologically in hospital were selected as the research subjects, whose pathological classification occurs with obvious low signal on T2WI. First, the age distribution of the subjects and the distribution of different subtypes were counted. Then, ANOVA was adopted to analyze the MRI imaging signs of patients with different subtypes of meningioma. Finally, the differences of Ki67, VEGF, and P73 proteins and mRNA expression levels in different subtypes were detected via immunohistochemical assay and qPCR. The results showed that the proportion of patients with transitional meningioma was the most, which was 43.28%, while the proportion of patients with meningeal melanoma was the least, which was 7.46%. In patients with transitional meningioma, the MRI images showed mixed signals in different layers. Fibrous MRI images showed hyalinosis and calcification of collagen fibers in the tumor, with low T2WI signal. Sand-shape MRI images showed double low signals. MRI images of meningeal melanoma showed high signal on T1-weighted Imaging (T1WI) and low signal on T2WI. The protein expression and mRNA levels of Ki67 and P73 in transitional meningioma were evidently higher in contrast to those in fibrous meningioma (

Indexed as

AdultAgedBiomarkers, TumorDiagnosis, DifferentialFemaleFollow-Up StudiesHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMelanomaMeningeal NeoplasmsMeningiomaMiddle AgedPrognosisYoung AdultBiomarkers, Tumor

Identifiers

PMID34354552
PMCPMC8292045
OpenAlexW3179851430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.