ArticleSaudi journal of biological sciences2021
β-Caryophyllene ameliorates the Mycoplasmal pneumonia through the inhibition of NF-κB signal transduction in mice.
Article in Saudi journal of biological sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 9 citations in OpenAlex.
- ADME/Tox study and the effect of β-Caryophyllene on the resistant strain ofToxicology reports · 2025Article
- Plants from Arid and Semi-Arid Zones of Mexico Used to Treat Respiratory Diseases: A Review.Plants (Basel, Switzerland) · 2024Review
- Article
- β-Caryophyllene Ameliorates Cyclophosphamide Induced Cardiac Injury: The Association of TLR4/NFκB and Nrf2/HO1/NQO1 Pathways.Journal of cardiovascular development and disease · 2022Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPneumonia is a frequent infectious disease that mainly affects the children and the global death rate is nearly 19% among children at the below 5 age. β-caryophyllene is an active compound, mainly occurs in the spices and it possesses immense biological activities.
objectiveThis investigation deliberated to scrutinize the beneficial actions of β-caryophyllene against the
methodsThe pneumonia was stimulated to the BALB/c mice by infecting them with 100 µl of
resultsThe β-caryophyllene notably diminished the total protein status, total cell count, and bacterial load in the pneumonia provoked mice. The marked reduction in the status of pro-inflammatory regulators was seen in the β-caryophyllene supplemented pneumonia mice. β-caryophyllene also down-regulated the expression of NF-ƙB thereby reduced the lung inflammation and tissue damages as seen in the result of histological analysis.
conclusionThese findings were confirmed the therapeutic potential of β-caryophyllene against the
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Registered trials
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