Evidence map›Paper›PMID 34354190›Full record

ArticleScientific reports2021

Unbiased, comprehensive analysis of Japanese health checkup data reveals a protective effect of light to moderate alcohol consumption on lung function.

Kanako Makino, Ryoko Shimizu-Hirota, Norio Goda, Masahiro Hashimoto, Ichiro Kawada, Kazuhiro Kashiwagi, Yasushi Hirota, Hiroshi Itoh, Masahiro Jinzaki, Yasushi Iwao and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

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  9. The association between alcohol consumption and pulmonary function: a scoping review.European respiratory review : an official journal of the European Respiratory Society · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Kanako MakinoCenter for Preventive Medicine, School of Medicine, Keio University, Tokyo, Japan.
Ryoko Shimizu-HirotaCenter for Preventive Medicine, School of Medicine, Keio University, Tokyo, Japan. rshimizu@keio.jp.
Norio GodaDepartment of Systems Medicine, School of Medicine, Keio University, Tokyo, Japan.
Masahiro HashimotoDepartment of Radiology, School of Medicine, Keio University, Tokyo, Japan.
Ichiro KawadaDepartment of Pulmonary Medicine, School of Medicine, Keio University, Tokyo, Japan.
Kazuhiro KashiwagiCenter for Preventive Medicine, School of Medicine, Keio University, Tokyo, Japan.
Yasushi HirotaDepartment of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Hiroshi ItohDepartment of Nephrology, Endocrinology and Metabolism, School of Medicine, Keio University, Tokyo, Japan.
Masahiro JinzakiDepartment of Radiology, School of Medicine, Keio University, Tokyo, Japan.
Yasushi IwaoCenter for Preventive Medicine, School of Medicine, Keio University, Tokyo, Japan.
Minoru KoDepartment of Systems Medicine, School of Medicine, Keio University, Tokyo, Japan.
Shigeru KoDepartment of Systems Medicine, School of Medicine, Keio University, Tokyo, Japan.
Hiromasa TakaishiCenter for Preventive Medicine, School of Medicine, Keio University, Tokyo, Japan.
Keio University · JPThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The overall effect of lifestyle habits, such as alcohol consumption, on general health remains controversial and it is important to clarify how such habits affect aging-related health impairments. To discover novel impacts of lifestyle on general health, we employed a mathematical approach to perform a comprehensive, unbiased, cross-sectional analysis of data from 6036 subjects who participated in a Japanese health checkup. Notably, we found that moderate alcohol consumption was positively correlated with lung function, muscle mass, and strength. Health checkup data were collected periodically from the same subjects. These people were light to moderate drinkers who had high health awareness and were basically free of major underlying diseases. We next analyzed 5 years of data from 1765 of these subjects. We found that higher baseline alcohol consumption, as well as increased alcohol intake over 5 years attenuated time-related deterioration of forced vital capacity without affecting total lung volume. This effect was independent of smoking. Our study suggests a possible protective effect of moderate amounts of alcohol on lung function, due to increased muscle mass/strength and forced vital capacity.

Indexed as

AgedAgingAlcohol DrinkingCross-Sectional StudiesElectronic Health RecordsEthanolFemaleHealthHealth BehaviorHumansJapanLungMaleMiddle AgedModels, TheoreticalProtective AgentsEthanolProtective Agents

Identifiers

PMID34354190
PMCPMC8342527
OpenAlexW3189987070

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.