ArticleScientific reports2021
Dodecanol, metabolite of entomopathogenic fungus Conidiobolus coronatus, affects fatty acid composition and cellular immunity of Galleria mellonella and Calliphora vicina.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 33 citations in OpenAlex.
- Valorization of Agave potatorum byproducts as a source of volatile α-glucosidase inhibitors.Journal of the science of food and agriculture · 2026Article
- Insecticidal and immunotoxic actions of 2-octenoic acid in the green bottle fly Lucilia sericata (Diptera: Calliphoridae).Medical and veterinary entomology · 2026Article
- Assessment of freeze-dried Sargassum polycystum as a nutritional feed component for red tilapia (Oreochromis spp.) fingerlings.Scientific reports · 2025Article
- Article
- Morphological and Chemical Changes in the Hemolymph of the Wax MothPathogens (Basel, Switzerland) · 2025Article
- Article
- Effect of Benzyl Alcohol on Main Defense System Components ofInternational journal of molecular sciences · 2024Article
- Oxidative stress is intrinsic to staphylococcal adaptation to fatty acid synthesis antibiotics.iScience · 2024Article
- The Entomopathogenic FungusInsects · 2023Article
- Feasibility of using volatile urine fingerprints for the differentiation of sexually transmitted infections.Applied microbiology and biotechnology · 2023Article
- Article
- Computer-aided identification ofFrontiers in pharmacology · 2023Article
- Lipids as a key element of insect defense systems.Frontiers in genetics · 2023Review
- Insect cuticular compounds affect Conidiobolus coronatus (Entomopthorales) sporulation and the activity of enzymes involved in fungal infection.Scientific reports · 2022Article
- Octanoic Acid-An Insecticidal Metabolite ofInternational journal of molecular sciences · 2022Article
- Review
- The Impact of the Entomopathogenic FungusInsects · 2021Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One group of promising pest control agents are the entomopathogenic fungi; one such example is Conidiobolus coronatus, which produces a range of metabolites. Our present findings reveal for the first time that C. coronatus also produces dodecanol, a compound widely used to make surfactants and pharmaceuticals, and enhance flavors in food. The main aim of the study was to determine the influence of dodecanol on insect defense systems, i.e. cuticular lipid composition and the condition of insect immunocompetent cells; hence, its effect was examined in detail on two species differing in susceptibility to fungal infection: Galleria mellonella and Calliphora vicina. Dodecanol treatment elicited significant quantitative and qualitative differences in cuticular free fatty acid (FFA) profiles between the species, based on gas chromatography analysis with mass spectrometry (GC/MS), and had a negative effect on G. mellonella and C. vicina hemocytes and a Sf9 cell line in vitro: after 48 h, almost all the cells were completely disintegrated. The metabolite had a negative effect on the insect defense system, suggesting that it could play an important role during C. coronatus infection. Its high insecticidal activity and lack of toxicity towards vertebrates suggest it could be an effective insecticide.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.