ArticleScientific reports2021
The immune status, oxidative and epigenetic changes in tissues of turkeys fed diets with different ratios of arginine and lysine.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Effects of Digestible Arginine Supplementation in Low-Crude-Protein Diets on Productive Performance, Egg Quality Traits and Immune Response in Breeding Japanese Quails.Veterinary medicine and science · 2026Article
- Effects of fermented Arundo donax juice on growth performance, immunocompetence, antioxidant capacity, and intestinal digestive enzyme activity in Arbor Acres broilers.Tropical animal health and production · 2026Article
- The relationship between pollen monodiets and the activities of proteolytic systems in the fat body and hemolymph of honeybee workers.PloS one · 2025Article
- Dietary Artemisia Ordosica Polysaccharide Enhances Spleen and Intestinal Immune Response of Broiler Chickens.Biology · 2023Article
- Increased arginine, lysine, and methionine levels can improve the performance, gut integrity and immune status of turkeys but the effect is interactive and depends on challenge conditions.Veterinary research · 2022Article
- Article
- Increased Dietary Inclusion Levels of Lysine Are More Effective than Arginine in Supporting the Functional Status of the Gut in Growing Turkeys.Animals : an open access journal from MDPI · 2021Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the present experiment, it was assumed that the appropriate dietary ratio of arginine (Arg) to lysine (Lys) can improve the immune status and growth performance of turkeys. The aim of this study was to evaluate the effects of two inclusion rates of Arg relative to Lys in turkey diets with Lys content consistent with National Research Council (NRC) recommendations or 10% higher on the immune status of birds and indicators of protein and DNA damage due to oxidation, nitration or epigenetic changes. Another goal was to determine which dietary Arg:Lys ratio stimulates the immune response of turkeys vaccinated against Ornithobacterium rhinotracheale. The experiment was performed on 576 turkeys randomly assigned to four groups with two levels of Lys (low = NRC recommendation or high = NRC + 10%) and two levels of Arg (95% or 105% Arg relative to the content of dietary Lys). It was found that the Lys content of turkey diets should be 10% higher than that recommended by the NRC and combined with the higher Arg level (105% of Lys). Although the above Arg:Lys ratio did not improve the growth performance of birds, it stimulated their immune system and reduced protein nitration as well as protein and DNA oxidation.
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