ArticleAJNR. American journal of neuroradiology2021
Comparison of Hippocampal Subfield Segmentation Agreement between 2 Automated Protocols across the Adult Life Span.
Article in AJNR. American journal of neuroradiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.
- Age-related differences in hippocampal subfield volumes across the human lifespan: A meta-analysis.Hippocampus · 2023Pooled it
- Selective correlation of hippocampal volumes with WADA memory scores in mesial temporal sclerosis patients.Frontiers in neurology · 2025Article
- Hippocampal Structures Among Japanese Adolescents Before and After the COVID-19 Pandemic.JAMA network open · 2024Article
- Association of Hippocampal Subfield Volumes with Amyloid-Beta Deposition in Alzheimer's Disease.Journal of clinical medicine · 2022Article
- Polygenic score for Alzheimer's disease identifies differential atrophy in hippocampal subfield volumes.PloS one · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
Abstract
background and purposeThe hippocampus is a frequent focus of quantitative neuroimaging research, and structural hippocampal alterations are related to multiple neurocognitive disorders. An increasing number of neuroimaging studies are focusing on hippocampal subfield regional involvement in these disorders using various automated segmentation approaches. Direct comparisons among these approaches are limited. The purpose of this study was to compare the agreement between two automated hippocampal segmentation algorithms in an adult population. MATERIALS AND
methodsWe compared the results of 2 automated segmentation algorithms for hippocampal subfields (FreeSurfer v6.0 and volBrain) within a single imaging data set from adults (
resultsEstimated intracranial volume and total hippocampal volume of both protocols were strongly correlated (
conclusionsThe hippocampal subfield volume relationship to demographic factors and disease states should undergo nuanced interpretation, especially when considering different segmentation protocols.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.