Evidence map›Paper›PMID 34353692›Full record

ArticleJournal of Ayurveda and integrative medicine

In vitro antiplasmodial activity, cytotoxicity, and gas chromatography - flame ionization detector metabolites fingerprint of extracts and fractions from Tetrorchidium didymostemon.

Osamudiamen Ebohon, Francis Irabor, Nekpen Erhunse, Abigail Omagene, Ehimwenma Sheena Omoregie

Abstract read
In one paragraph

Article in Journal of Ayurveda and integrative medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Osamudiamen EbohonMichael and Cecilia Ibru University, Faculty of Natural and Applied Sciences, Department of Biological and Chemical Sciences, Biochemistry Program, P.M.B. 100, Agbarha-Otor, Delta State, Nigeria. Electronic address: ebohonosamudiamen@yahoo.com.
Francis IraborMichael and Cecilia Ibru University, Faculty of Natural and Applied Sciences, Department of Biological and Chemical Sciences, Biochemistry Program, P.M.B. 100, Agbarha-Otor, Delta State, Nigeria.
Nekpen ErhunseUniversity of Benin, Faculty of Life Sciences, Department of Biochemistry, Malaria Research, Molecular Biology and Toxicology Unit, P.M.B 1154, Benin City, Nigeria; International Centre for Genetic Engineering and Biotechnology, Malaria Drug Discovery Research Group, New Delhi, 110067, India.
Abigail OmageneUniversity of Benin, Faculty of Life Sciences, Department of Biochemistry, Malaria Research, Molecular Biology and Toxicology Unit, P.M.B 1154, Benin City, Nigeria.
Ehimwenma Sheena OmoregieUniversity of Benin, Faculty of Life Sciences, Department of Biochemistry, Malaria Research, Molecular Biology and Toxicology Unit, P.M.B 1154, Benin City, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTetrorchidium didymostemon is used as an antimalarial remedy in southern Nigeria. OBJECTIVE(S): This study was aimed at providing scientific validation for the use of T. didymostemon in the treatment of malaria in Nigeria. MATERIALS AND

methodsPlasmodium falciparum 3D7 (Pf3D7) strain was cultured and maintained in fresh O

resultsThe methanol leaf extract had higher antiplasmodial activity (IC

conclusionThe results of our study validate the traditional use of T. didymostemon in the treatment of malaria in southern Nigeria. They also suggest that the phytoconstituent(s) responsible for the antiplasmodial activity of this plant may be more extractable in non-polar solvents.

Indexed as

AntioxidantEthnopharmacologyGC-FIDMalariaPhytoconstituentsTetrorchidium didymostemon

Identifiers

PMID34353692
PMCPMC8377187

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