Evidence map›Paper›PMID 34353350›Full record

ArticleGenome biology2021

Community-wide hackathons to identify central themes in single-cell multi-omics.

Kim-Anh Lê Cao, Al J Abadi, Emily F Davis-Marcisak, Lauren Hsu, Arshi Arora, Alexis Coullomb, Atul Deshpande, Yuzhou Feng, Pratheepa Jeganathan, Melanie Loth and 21 more

Erratum issuedAbstract readLetter
In one paragraph

Article in Genome biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Mapping multipathology via spatial omic integration.Current opinion in biotechnology · 2026
    Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

31 authors.

Kim-Anh Lê CaoMelbourne Integrative Genomics, School of Mathematics and Statistics, University of Melbourne, Melbourne, Australia. kimanh.lecao@unimelb.edu.au.
Al J AbadiMelbourne Integrative Genomics, School of Mathematics and Statistics, University of Melbourne, Melbourne, Australia.
Emily F Davis-MarcisakMcKusick-Nathans Institute of the Department of Genetic Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Lauren HsuData Science, Dana-Farber Cancer Institute, Boston, MA, USA.
Arshi AroraDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Alexis CoullombCentre de Recherches en Cancérologie de Toulouse (INSERM), Université Paul Sabatier III, Toulouse, France.
Atul DeshpandeCancer Convergence Institute and Division of Quantitative Sciences, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Yuzhou FengMelbourne Integrative Genomics, School of Mathematics and Statistics, University of Melbourne, Melbourne, Australia.
Pratheepa JeganathanDepartment of Mathematics and Statistics, McMaster University, Hamilton, Canada.
Melanie LothCancer Convergence Institute and Division of Quantitative Sciences, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Chen MengBavarian Center for Biomolecular Mass Spectrometry (BayBioMS), School of Life Sciences, Technical University of Munich, Munich, Germany.
Wancen MuDepartment of Biostatistics, UNC, Chapel Hill, NC, USA.
Vera PancaldiCentre de Recherches en Cancérologie de Toulouse (INSERM), Université Paul Sabatier III, Toulouse, France.
Kris SankaranDepartment of Statistics, University of Wisconsin, Madison, WI, USA.
Dario RighelliDepartment of Statistical Sciences, University of Padova, Padova, PD, Italy.
Amrit SinghDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.
Joshua S SodicoffDepartment of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
Genevieve L Stein-O'BrienMcKusick-Nathans Institute of the Department of Genetic Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Ayshwarya SubramanianKlarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Joshua D WelchDepartment of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.
Yue YouEpigenetics and Development Division, The Walter and Eliza Hall Institute of Medical Research, University of Melbourne, Melbourne, Australia.
Ricard ArgelaguetEpigenetics Programme, Babraham Institute, Cambridge, CB22 3AT, UK.
Vincent J CareyChanning Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Ruben DriesDepartment of Hematology and Oncology, Boston Medical Center, Boston, MA, USA.
Casey S GreeneCenter for Health AI and Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, CO, USA.
Susan HolmesDepartment of Statistics, Stanford University, Stanford, CA, USA.
Michael I LoveDepartment of Biostatistics, UNC, Chapel Hill, NC, USA.
Matthew E RitchieEpigenetics and Development Division, The Walter and Eliza Hall Institute of Medical Research, University of Melbourne, Melbourne, Australia.
Guo-Cheng YuanDepartment of Genetics and Genomic Sciences, Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Aedin C CulhaneData Science, Dana-Farber Cancer Institute, Boston, MA, USA.
Elana FertigCancer Convergence Institute and Division of Quantitative Sciences, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Tissue Procurement & PathologyP50CA058223 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHARLES M PEROU · 1992 to 2026
$59.3M
Supplement: Enhancing Community Contributions to Bioconductor With Build System Containerization and a GPU for TestingU24HG004059 · NHGRI · DANA-FARBER CANCER INST · PI VINCENT JAMES CAREY, Rafael Angel Irizarry · 2021 to 2026
$7.3M
Quantitative definition of cell identity from single-cell multi-omic, spatial, and perturbation dataR01HG010883 · NHGRI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Joshua Welch · 2019 to 2026
$4.4M
Single-cell and imaging data integration software to spatially resolve the tumor microenvironmentU01CA253403 · NCI · JOHNS HOPKINS UNIVERSITY · PI FERTIG, ELANA · 2020 to 2022
$1.2M
Resolving Spatiotemporal Determinants of Cell Specification in Corticogenesis with Latent Space MethodsR00NS122085 · NINDS · JOHNS HOPKINS UNIVERSITY · PI STEIN-O'BRIEN, GENEVIEVE LAUREN · 2023 to 2025
$697k
In situ transcriptome profiling in single cellsUH3CA255134 · NCI · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI CAI, LONG, YUAN, GUO-CHENG · 2020 to 2020
$400k
Resolving Spatiotemporal Determinants of Cell Specification in Corticogenesis with Latent Space MethodsK99NS122085 · NINDS · JOHNS HOPKINS UNIVERSITY · PI STEIN-O'BRIEN, GENEVIEVE LAUREN · 2021 to 2022
$221k
NCI NIH HHS P30 CA008748NCI NIH HHS P50 CA058223NCI NIH HHS U01 CA253403NCI NIH HHS UH3 CA255134NHGRI NIH HHS R01 HG010883NHGRI NIH HHS U24 HG004059NINDS NIH HHS K99 NS122085NINDS NIH HHS R00 NS122085
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Computational BiologySingle-Cell AnalysisHumansProteomicsSoftwareTranscriptome

Identifiers

PMID34353350
PMCPMC8340473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.