ReviewCritical care (London, England)2021
Breathing variability-implications for anaesthesiology and intensive care.
Review in Critical care (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed.
- Find your rhythm and regulate: Breath-synced vibration feedback during breath-focused mindfulness reduces respiration variability in trauma-exposed adults.Journal of anxiety disorders · 2025Trial
- Effects of s-ketamine and midazolam on respiratory variability: A randomized controlled pilot trial.PloS one · 2025Trial
- A novel therapeutic regimen based on the constrained-disorder principles may improve the response to dimethyl fumarate in multiple sclerosis: Findings from an exploratory feasibility open-label clinical trial.IBRO neuroscience reports · 2026Article
- Autonomic Network Signatures of Interictal Cardiorespiratory Dysfunction in Patients With Temporal Lobe Epilepsy.Neurology · 2026Article
- Toward Free-Breathing Renal CEST MRI: Preclinical Evaluation of a Novel Prospective Respiratory Triggering Approach.Magnetic resonance in medicine · 2026Article
- Fucose-tobramycin sponge-like microparticles to treat pulmonary Pseudomonas aeruginosa infections in a lectin-competitive approach.Journal of advanced research · 2026Article
- Personalization of Caffeine Therapy for Apnea of Prematurity: A Potential Role for Sensor Technologies?Sensors (Basel, Switzerland) · 2026Review
- AI-enabled wireless wearable breathing sensor for breathing pattern recognition.Scientific reports · 2026Article
- Respiratory Variability in Disorders of Consciousness: Relationship and Clinical Applications.CNS neuroscience & therapeutics · 2026Article
- Respiratory-Limbic Coupling via a Thalamic Circuit Alleviates Anxiety.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Using objective measures of physical activity, sleep, and breathing for disease profiling of patients with systemic lupus erythematosus and Sjögren's disease.Frontiers in digital health · 2026Article
- Variability in Exercise is Linked to Improved Age-related Dysfunctions, Suggesting a Potential Role for the Constrained-Disorder Principle-based Second-Generation Artificial Intelligence System.Current aging science · 2026Article
- Inspiratory effort increases blood volume in the thoracic cavity and decreases end-expiratory lung impedance: a preliminary prospective study.European journal of applied physiology · 2025Article
- Neurally adjusted ventilatory assist in critical care patients with and without obesity: a prospective randomized crossover study.Annals of intensive care · 2025Article
- Wearable Device-Based Respiratory Complexity Analysis for Detecting Pulmonary Congestion in Patients With Heart Failure: Observational Exploratory Study.Journal of medical Internet research · 2025Observational
- Different effects of epidural versus paravertebral analgesia on respiratory rate variability after oesophagectomy: A single-centre observational subanalysis from the PEPMEN trial.European journal of anaesthesiology and intensive care · 2025Article
- Review
- The association of ventilator mechanical power with weaning outcomes in intensive care unit patients: a narrative review.Journal of thoracic disease · 2025Review
- Exploratory Analysis of Respiratory Variability in Relation to Disease Impact, Affective Symptoms, and Pain Sensitivity in Fibromyalgia.Journal of pain research · 2025Article
- The Constrained Disorder Principle Overcomes the Challenges of Methods for Assessing Uncertainty in Biological Systems.Journal of personalized medicine · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The respiratory system reacts instantaneously to intrinsic and extrinsic inputs. This adaptability results in significant fluctuations in breathing parameters, such as respiratory rate, tidal volume, and inspiratory flow profiles. Breathing variability is influenced by several conditions, including sleep, various pulmonary diseases, hypoxia, and anxiety disorders. Recent studies have suggested that weaning failure during mechanical ventilation may be predicted by low respiratory variability. This review describes methods for quantifying breathing variability, summarises the conditions and comorbidities that affect breathing variability, and discusses the potential implications of breathing variability for anaesthesia and intensive care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.