Evidence map›Paper›PMID 34353202›Full record

ReviewJournal of enzyme inhibition and medicinal chemistry2021

Cyanobacteria and microalgae bioactive compounds in skin-ageing: potential to restore extracellular matrix filling and overcome hyperpigmentation.

Rita Favas, Janaína Morone, Rosário Martins, Vitor Vasconcelos, Graciliana Lopes

Open access · goldAbstract readReview
In one paragraph

Review in Journal of enzyme inhibition and medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 54 citations in OpenAlex.

  1. The DiatomAntioxidants (Basel, Switzerland) · 2025
    Article
  2. Microalgae: revolutionizing skin repair and enhancement.Biotechnology reports (Amsterdam, Netherlands) · 2025
    Review
  3. Review
  4. Review
  5. The Effects of Physical Activity on Skin Health: A Narrative Review.Clinical, cosmetic and investigational dermatology · 2025
    Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. SNA077, an Extract of MarineInternational journal of molecular sciences · 2022
    Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rita FavasCIIMAR/CIMAR, Interdisciplinary Centre of Marine and Environmental Research, Matosinhos, Portugal.
Janaína MoroneCIIMAR/CIMAR, Interdisciplinary Centre of Marine and Environmental Research, Matosinhos, Portugal.ORCID https://orcid.org/0000-0002-9869-1692
Rosário MartinsCIIMAR/CIMAR, Interdisciplinary Centre of Marine and Environmental Research, Matosinhos, Portugal.ORCID https://orcid.org/0000-0002-9882-4651
Vitor VasconcelosCIIMAR/CIMAR, Interdisciplinary Centre of Marine and Environmental Research, Matosinhos, Portugal.ORCID https://orcid.org/0000-0003-3585-2417
Graciliana LopesCIIMAR/CIMAR, Interdisciplinary Centre of Marine and Environmental Research, Matosinhos, Portugal.ORCID https://orcid.org/0000-0002-7764-474X
Universidade do Porto · PTCentro Interdisciplinar de Investigação Marinha e Ambiental

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the largest organ in human body, skin acts as a physicochemical barrier, offering protection against harmful environmental stressors, such as chemicals, pathogens, temperature and radiation. Nonetheless, skins prominence goes further, with a significant psychosocial role in an increasingly ageing population. Prompted by consumers' concern regarding skincare, cosmetic industry has been developing new formulas capable of lessening the most visible signs of ageing, including reduction in skin density and elasticity, wrinkling and hyperpigmentation. Allied to skincare is the rising importance set on natural products, sustainably obtained from less environmental impacting methods. Cyanobacteria and microalgae are adding importance in this field, given their ability to biosynthesize secondary metabolites with anti-ageing potential. In this review, we present an overview on the potential of cyanobacteria and microalgae compounds to overcome skin-ageing, essentially by exploring their effects on the metalloproteinases collagenase, elastase, gelatinase and hyaluronidase, and in other enzymes involved in the pigmentation process.

Indexed as

AntioxidantsBiological ProductsCollagenasesComplex MixturesCyanobacteriaExtracellular MatrixGelatinasesHumansHyaluronoglucosaminidaseHyperpigmentationMetalloproteasesMicroalgaePancreatic ElastaseSkinSkin AgingAntioxidantsBiological ProductsCollagenasesComplex MixturesGelatinasesHyaluronoglucosaminidaseMetalloproteasesPancreatic Elastasecollagenaseelastasehyaluronidasehyperpigmentationmatrix metalloproteinasesSkin ageing

Identifiers

PMID34353202
PMCPMC8354154
OpenAlexW3191840371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.