Evidence map›Paper›PMID 34352586›Full record

ReviewNutrition (Burbank, Los Angeles County, Calif.)

The possible benefits of vitamin D in COVID-19.

Danilo Társio Mota Brito, Luiza Helena Coutinho Ribeiro, Carla Hilário da Cunha Daltro, Roberto de Barros Silva

Open access · greenAbstract readReview
In one paragraph

Review in Nutrition (Burbank, Los Angeles County, Calif.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Danilo Társio Mota BritoMedicine Department, Salvador University, Salvador, Brazil.
Luiza Helena Coutinho RibeiroMedicine Department, Salvador University, Salvador, Brazil.
Carla Hilário da Cunha DaltroMedicine Department, Federal University of Bahia, Salvador, Brazil.
Roberto de Barros SilvaMedicine Department, Salvador University, Salvador, Brazil. Electronic address: roberto.barros@unifacs.br.
Universidade Salvador · BRUniversidade Federal da Bahia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molecular studies have demonstrated the importance of the exacerbated immune response to SARS-CoV-2 infection, called the cytokine storm, in more severe COVID-19. The pathophysiology is complex and involves several homeostatic factors; among them, a deficit of vitamin D draws attention because of its high frequency in the population. Some evidence suggests that people with low serum vitamin D levels have worse outcomes, often requiring intensive care. This review analyzed the studies available in the global literature addressing the benefits of vitamin D in COVID-19, relating serum levels to the severity of the disease, and indicating vitamin D as a possible prophylactic and therapy in infection.

Indexed as

COVID-19Vitamin D DeficiencyCytokine Release SyndromeHumansSARS-CoV-2Vitamin DVitaminsVitamin DVitaminsCOVID-19Cytokine stormImmunomodulationVitamin D

Identifiers

PMID34352586
PMCPMC8149468
OpenAlexW3165022478

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.