Evidence map›Paper›PMID 34352474›Full record

ReviewCurrent opinion in virology2021

COVID-19, the first pandemic in the post-genomic era.

Lucy van Dorp, Charlotte J Houldcroft, Damien Richard, François Balloux

Abstract readReview
In one paragraph

Review in Current opinion in virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. SARS-CoV-2 immunity.Cellular & molecular immunology · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Stability and expression of SARS-CoV-2 spike-protein mutations.Molecular and cellular biochemistry · 2023
    Article
  12. Article
  13. Initial immune response after exposure toFrontiers in immunology · 2023
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Editorial overview: Viral pathogenesis.Current opinion in virology · 2022
    Article
  19. Article
  20. A fractal scaling analysis of the SARS-CoV-2 genome sequence.Biomedical signal processing and control · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lucy van DorpUCL Genetics Institute, Department of Genetics, Evolution and Environment, University College London, London, WC1E 6BT, UK. Electronic address: lucy.dorp.12@ucl.ac.uk.
Charlotte J HouldcroftDepartment of Medicine, University of Cambridge, Cambridge, CB2 1TN, UK.
Damien RichardUCL Genetics Institute, Department of Genetics, Evolution and Environment, University College London, London, WC1E 6BT, UK; Division of Infection and Immunity, University College London, London, WC1E 6BT, UK.
François BallouxUCL Genetics Institute, Department of Genetics, Evolution and Environment, University College London, London, WC1E 6BT, UK.

Funding

Biotechnology and Biological Sciences Research Council BB/R01356X/1Wellcome Trust 204870/Z/16/Z
6 · The paper itself

Abstract

The scale of the international efforts to sequence SARS-CoV-2 genomes is unprecedented. Early availability of genomes allowed rapid characterisation of the virus, thus kickstarting many highly successful vaccine development programmes. Worldwide genomic resources have provided a good understanding of the pandemic, supported close monitoring of the emergence of viral genomic diversity and pinpointed those sites to prioritise for functional characterisation. Continued genomic surveillance of global viral populations will be crucial to inform the timing of vaccine updates so as to pre-empt the spread of immune escape lineages. While genome sequencing has provided us with an exceptionally powerful tool to monitor the evolution of SARS-CoV-2, there is room for further improvements in particular in the form of less heterogeneous global surveillance and tools to rapidly identify concerning viral lineages.

Indexed as

Genome, ViralCell LineageCOVID-19Evolution, MolecularHumansMutationSARS-CoV-2

Identifiers

PMID34352474
PMCPMC8275481

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.