Evidence map›Paper›PMID 34352259›Full record

ArticleLife sciences2022

A common language for Gulf War Illness (GWI) research studies: GWI common data elements.

Devra E Cohen, Kimberly A Sullivan, Rebecca B McNeil, Gulf War Illness Common Data Elements Working Group:, Symptoms Assessment Working Group:, Rebecca B McNeil, Wes Ashford, Alison Bested, James Bunker, Amanpreet Cheema and 48 more

Abstract read
In one paragraph

Article in Life sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

58 authors.

Devra E CohenMiami VA Healthcare System, Miami, FL, United States; Institute for Neuro Immune Medicine, Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL, United States. Electronic address: devra.cohen@va.gov.
Kimberly A SullivanDepartment of Environmental Health, Boston University School of Public Health, Boston, MA, United States.
Rebecca B McNeilRTI International, Research Triangle Park, NC, United States.
Gulf War Illness Common Data Elements Working Group:
Symptoms Assessment Working Group:
Rebecca B McNeilRTI International, Research Triangle Park, NC, United States.
Wes AshfordWar Related Illness and Injury Study Center, VA Palo Healthcare System, Palo Alto, CA, United States.
Alison BestedInstitute for Neuro Immune Medicine, Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL, United States.
James BunkerNational Gulf War Resource Center, Inc., Topeka, KS, United States.
Amanpreet CheemaInstitute for Neuro Immune Medicine, Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL, United States.
Devra E CohenMiami VA Healthcare System, Miami, FL, United States; Institute for Neuro Immune Medicine, Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL, United States.
Dane CookUniversity of Wisconsin-Madison, Madison, WI, United States.
Jeffrey CournoyerInstitute for Neuro Immune Medicine, Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL, United States.
Travis CraddockInstitute for Neuro Immune Medicine, Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL, United States.
Julia GolierJames J. Peters VA Medical Center; Icahn School of Medicine at Mount Sinai, Bronx, NY, United States.
Anthony HardieVeterans for Common Sense and former U.S. Army, Bradenton, FL, United States.
Drew HelmerMichael E. DeBakey VA Medical Center, Houston, TX, United States.
Jacob B LindheimerWilliam S. Middleton Veterans Memorial Hospital, University of Wisconsin- Madison, Madison, WI, United States.
Patricia Janulewicz LloydBoston University, Boston, MA, United States.
Kathleen KerrUniversity of Toronto, Toronto, Canada.
Maxine KrengelBoston VA Healthcare System; Boston University, Boston, MA, United States.
Shree NadkarniWar Related Illness and Injury Study Center, VA New Jersey Health Care System, East Orange, NJ, United States.
Shannon NugentVA Portland Health Care System, Portland, OR, United States.
Bonnie ParisVA Information Resource Center (VIReC), Hines, IL, United States.
Matthew ReinhardWar Related Illness and Injury Study Center, Washington DC VA Medical Center, Washington, DC, United States.
Peter RummUnited States Department of Veterans Affairs, Washington, DC, United States.
Aaron SchneidermanUnited States Department of Veterans Affairs, Washington, DC, United States.
Kellie J SimsCooperative Studies Program Epidemiology Center, Durham VA Medical Center, Durham, NC, United States.
Lea SteeleBaylor College of Medicine, Houston, TX, United States.
Marsha TurnerCooperative Studies Program Epidemiology Center, Durham VA Medical Center, Durham, NC, United States.
Systems Assessment Working Group:
Kimberly A SullivanDepartment of Environmental Health, Boston University School of Public Health, Boston, MA, United States.
Laila AbdullahRoskamp Institute, Sarasota, FL, United States.
Maria AbreuMiami VA Healthcare System, Miami, FL, United States; Institute for Neuro Immune Medicine, Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL, United States.
Mohamed Abu-DoniaDuke University Medical Center, Durham, NC, United States.
Kristina AenlleMiami VA Healthcare System, Miami, FL, United States; Institute for Neuro Immune Medicine, Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL, United States.
Jimmy ArochoInstitute for Neuro Immune Medicine, Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL, United States; United States Army (Retired), United States.
Elizabeth BalbinMiami VA Healthcare System, Miami, FL, United States; Institute for Neuro Immune Medicine, Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL, United States.
James BaraniukGeorgetown University, Washington, DC, United States.
Karen BlockOffice of Research and Development, US Department of Veterans Affairs, Washington, DC, United States.
Michelle BlockIndiana University, Indianapolis, IN, United States.
Bryann DeBeerTexas A&M Health Science Center, Central Texas Veterans Healthcare System, Waco, TX, United States.
Brian EngdahlMinneapolis VA Health Care System, University of Minnesota, Minneapolis, MN, United States.
Nikolay FilipovUniversity of Georgia, Atlanta, GA, United States.
Mary Ann FletcherInstitute for Neuro Immune Medicine, Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL, United States.
Victor KalasinskyOffice of Research and Development, US Department of Veterans Affairs, Washington, DC, United States.
Efi KokkotouHarvard University, Beth Israel Deaconess Medical Center, Boston, MA, United States.
Kristy LidieUnited States Army and Medical Research and Material Command, Fort Detrick, MD, United States.
Deborah LittleBaylor College of Medicine, Houston, TX, United States.
William LogingUnited States Marine Corps (Retired), Ft. Lauderdale, FL, United States.
Marianna MorrisInstitute for Neuro Immune Medicine, Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL, United States.
Lubov NathansonInstitute for Neuro Immune Medicine, Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL, United States.
Montra Denise NicholsUnited States Air Force (Retired), United States.
Giulio PasinettiIcahn School of Medicine at Mount Sinai, Bronx, NY, United States.
Dikoma ShunguWeill Cornell Medical Center, New York, NY, United States.
Paula WaziryNova Southeastern University, Ft. Lauderdale, FL, United States.
Jon VanLeeuwenUniversity of California, VA Research Advisory Committee on Gulf War Veterans' Illnesses, San Francisco, CA, United States.
Jarred YoungerThe University of Alabama, Birmingham, AL, United States.

Funding

Translational Research Support CoreP30ES030285 · NIEHS · BAYLOR COLLEGE OF MEDICINE · PI Casey W Wright · 2019 to 2026
$14.7M
Acute exercise tolerance among Veterans with Gulf War IllnessIK2CX001679 · VA · WM S. MIDDLETON MEMORIAL VETERANS HOSP · PI LINDHEIMER, JACOB · 2018 to 2023
–
CSRD VA IK2 CX001679CSRD VA IK6 CX002369NIEHS NIH HHS P30 ES030285
6 · The paper itself

Abstract

aimsThe Gulf War Illness programs (GWI) of the United States Department of Veteran Affairs and the Department of Defense Congressionally Directed Medical Research Program collaborated with experts to develop Common Data Elements (CDEs) to standardize and systematically collect, analyze, and share data across the (GWI) research community. MAIN

methodsA collective working group of GWI advocates, Veterans, clinicians, and researchers convened to provide consensus on instruments, case report forms, and guidelines for GWI research. A similar initiative, supported by the National Institute of Neurologic Disorders and Stroke (NINDS) was completed for a comparative illness, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), and provided the foundation for this undertaking. The GWI working group divided into two sub-groups (symptoms and systems assessment). Both groups reviewed the applicability of instruments and forms recommended by the NINDS ME/CFS CDE to GWI research within specific domains and selected assessments of deployment exposures. The GWI CDE recommendations were finalized in March 2018 after soliciting public comments. KEY

findingsGWI CDE recommendations are organized in 12 domains that include instruments, case report forms, and guidelines. Recommendations were categorized as core (essential), supplemental-highly recommended (essential for specified conditions, study types, or designs), supplemental (commonly collected, but not required), and exploratory (reasonable to use, but require further validation). Recommendations will continually be updated as GWI research progresses. SIGNIFICANCE: The GWI CDEs reflect the consensus recommendations of GWI research community stakeholders and will allow studies to standardize data collection, enhance data quality, and facilitate data sharing.

Indexed as

Persian Gulf SyndromeBiomedical ResearchCommon Data ElementsHumansInformation DisseminationNational Institute of Neurological Disorders and Stroke (U.S.)United StatesUnited States Department of Veterans AffairsVeterans HealthCDECDMRPDoDGWGWIGWVVA

Identifiers

PMID34352259
PMCPMC9267452

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.