Evidence map›Paper›PMID 34351759›Full record

ArticleACS sensors2021

State of Sweat: Emerging Wearable Systems for Real-Time, Noninvasive Sweat Sensing and Analytics.

Roozbeh Ghaffari, Da Som Yang, Joohee Kim, Amer Mansour, John A Wright, Jeffrey B Model, Donald E Wright, John A Rogers, Tyler R Ray

Open access · greenAbstract read
In one paragraph

Article in ACS sensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
9.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 158 citations in OpenAlex.

  1. Review
  2. Microfluidic valves for wearable sweat analysis: a review.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Roozbeh GhaffariQuerrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, Illinois 60202, United States.
Da Som YangQuerrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, Illinois 60202, United States.
Joohee KimQuerrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, Illinois 60202, United States.
Amer MansourDivision of Biological Sciences, The University of Chicago, Chicago, Illinois 60637, United States.
John A WrightQuerrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, Illinois 60202, United States.
Jeffrey B ModelQuerrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, Illinois 60202, United States.
Donald E WrightEpicore Biosystems, Inc., Cambridge, Massachusetts 02139, United States.
John A RogersQuerrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, Illinois 60202, United States.ORCID 0000-0002-2980-3961
Tyler R RayDepartment of Mechanical Engineering, University of Hawai'i at Ma̅noa, Honolulu, Hawaii 96822, United States.ORCID 0000-0001-7047-9676
Northwestern University · USUniversity of Chicago · USUniversity of Hawaiʻi at Mānoa · US

Funding

TRPA1 Physiology in Diabetes, Metabolic Syndrome, and MetabolismP20GM113134 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI Michael A. Ortega · 2017 to 2026
$21.5M
Soft, Epidermal Biosystems with Advanced Sensing and Microfluidics Capabilities for Assessing Fatigability BiomarkersR43AG067835 · NIA · EPICORE BIOSYSTEMS, INC. · PI ARANYOSI, ALEXANDER J · 2020 to 2020
$252k
NIA NIH HHS R43 AG067835NIGMS NIH HHS P20 GM113134
6 · The paper itself

Abstract

Skin-interfaced wearable systems with integrated colorimetric assays, microfluidic channels, and electrochemical sensors offer powerful capabilities for noninvasive, real-time sweat analysis. This Perspective details recent progress in the development and translation of novel wearable sensors for personalized assessment of sweat dynamics and biomarkers, with precise sampling and real-time analysis. Sensor accuracy, system ruggedness, and large-scale deployment in remote environments represent key opportunity areas, enabling broad deployment in the context of field studies, clinical trials, and recent commercialization. On-body measurements in these contexts show good agreement compared to conventional laboratory-based sweat analysis approaches. These device demonstrations highlight the utility of biochemical sensing platforms for personalized assessment of performance, wellness, and health across a broad range of applications.

Indexed as

SweatWearable Electronic DevicesMicrofluidicsSkinbiosensorseccrine sweatepidermal microfluidicsflexible electronicshealth monitoringlab-on-chipsweat analysiswearable sensors

Identifiers

PMID34351759
PMCPMC9108092
OpenAlexW3189520890

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.