Evidence map›Paper›PMID 34351569›Full record

ArticleNeurotoxicity research2021

Suppression of Mitochondria-Related Bioenergetics Collapse and Redox Impairment by Tanshinone I, a Diterpenoid Found in Salvia miltiorrhiza Bunge (Danshen), in the Human Dopaminergic SH-SY5Y Cell Line Exposed to Chlorpyrifos.

Flávia Bittencourt Brasil, Fhelipe Jolner Souza de Almeida, Matheus Dargesso Luckachaki, Evandro Luiz Dall'Oglio, Marcos Roberto de Oliveira

Abstract read
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In one paragraph

Article in Neurotoxicity research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Flávia Bittencourt BrasilDepartment of Natural Sciences, Rio das Ostras Universitary Campus - Fluminense Federal University (UFF), Rio de Janeiro, Brazil.
Fhelipe Jolner Souza de AlmeidaGraduate Program in Health Sciences (PPGCS), Federal University of Mato Grosso (UFMT), Cuiaba, MT, Brazil.
Matheus Dargesso LuckachakiResearch Group in Neurochemistry and Neurobiology of Bioactive Molecules, Federal University of Mato Grosso (UFMT), Av. Fernando Corrêa da Costa, Cuiaba, MT, 2367, 78060-900, Brazil.
Evandro Luiz Dall'OglioResearch Group in Neurochemistry and Neurobiology of Bioactive Molecules, Federal University of Mato Grosso (UFMT), Av. Fernando Corrêa da Costa, Cuiaba, MT, 2367, 78060-900, Brazil.
Marcos Roberto de OliveiraResearch Group in Neurochemistry and Neurobiology of Bioactive Molecules, Federal University of Mato Grosso (UFMT), Av. Fernando Corrêa da Costa, Cuiaba, MT, 2367, 78060-900, Brazil. mrobioq@gmail.com.ORCID http://orcid.org/0000-0003-2414-6605
Universidade Federal de Mato Grosso · BRUniversidade Federal Fluminense · BR

Funding

conselho nacional de desenvolvimento científico e tecnológico Bolsista Produtividade PQ2 fellow protocol number 301273/2018-9conselho nacional de desenvolvimento científico e tecnológico Edital Universal 2016 protocol number 400216/2016-7
6 · The paper itself

Abstract

Tanshinone I (T-I, C

Indexed as

Salvia miltiorrhizaAbietanesCell Line, TumorCell SurvivalChlorpyrifosDopaminergic NeuronsDose-Response Relationship, DrugEnergy MetabolismHumansImmunosuppressive AgentsInsecticidesMitochondriaOxidation-ReductionAbietanesChlorpyrifosImmunosuppressive AgentsInsecticidestanshinoneAntioxidantChlorpyrifosHeme oxygenase-1MitochondriaNrf2Tanshinone I

Identifiers

PMID34351569
OpenAlexW3192632694

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.