Evidence map›Paper›PMID 34351519›Full record

ArticleInternational ophthalmology2021

Choroidal vascularity index in pseudoexfoliative glaucoma.

Melisa Zisan Karslioglu, Cem Kesim, Ozum Yucel, Ayse Yildiz Tas, Safak Torun, Cigdem Altan, Afsun Sahin

Abstract read
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In one paragraph

Article in International ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Melisa Zisan KarsliogluDepartment of Ophthalmology, School of Medicine, Koc University, Davutpasa Street, No 4, Postal code 34010, Zeytinburnu/Istanbul, Turkey.ORCID http://orcid.org/0000-0002-7665-4508
Cem KesimDepartment of Ophthalmology, School of Medicine, Koc University, Davutpasa Street, No 4, Postal code 34010, Zeytinburnu/Istanbul, Turkey.ORCID http://orcid.org/0000-0001-6747-1534
Ozum YucelBeyoglu Eye Training and Research Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-2687-3534
Ayse Yildiz TasDepartment of Ophthalmology, School of Medicine, Koc University, Davutpasa Street, No 4, Postal code 34010, Zeytinburnu/Istanbul, Turkey.ORCID http://orcid.org/0000-0003-1716-5488
Safak TorunSchool of Medicine, Koc University, Istanbul, Turkey.
Cigdem AltanBeyoglu Eye Training and Research Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-0908-6619
Afsun SahinDepartment of Ophthalmology, School of Medicine, Koc University, Davutpasa Street, No 4, Postal code 34010, Zeytinburnu/Istanbul, Turkey. afsunsahin@gmail.com.ORCID http://orcid.org/0000-0002-5083-5618
Koç University · TRIstanbul Eye Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate choroidal vascular involvement in pseudoexfoliative glaucoma (PEXG) by applying the choroidal vascularity index (CVI) to optic coherence tomography (OCT) images.

methodsSeventy-eight eyes from 40 subjects were included the study. Group 1 included healthy eyes (n = 20), group 2 eyes with PEX (n = 16), and group 3 eyes with PEXG (n = 42). OCT imaging of macular and peripapillary regions and retinal nerve fiber layer (RNFL) analyses were performed. CVI was calculated using ImageJ software.

resultsThe mean age was 64.89 ± 5.8, 71.2 ± 7.8, and 68.24 ± 7.4 years in groups 1, 2, and 3, respectively (p = 0.046). There were no significant differences between the groups in terms of sex (p = 0.777). In macula, mean CVI rates were 66.97 ± 1.9%, 64.23 ± 1.2%, and 64.63 ± 1.6%, and in the peripapillary areas, mean CVI rates were 67.04 ± 1.5%, 65.20 ± 1.5%, and 64.14 ± 2.1% in groups 1, 2, and 3, respectively (group 1 vs. group 2 and 3, p = 0.000; group 2 vs. group 3, p > 0.05). The decrease in average RNFL thickness was statistically significant in group 3 compared to groups 1 and 2.

conclusionCVI could be used to assess choroidal vascular changes in ocular diseases. CVI was found to be reduced in PEX and PEXG, indicating an ocular vascular involvement in pseudoexfoliative process.

Indexed as

GlaucomaMacula LuteaAgedChoroidHumansMiddle AgedTomography, Optical CoherenceChoroidal vascularity indexPseudoexfoliation syndromePseudoexfoliative glaucoma

Identifiers

PMID34351519
OpenAlexW3187871252

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.