SynthesisParasitology research2021
Genotype distribution of Acanthamoeba in keratitis: a systematic review.
Synthesis in Parasitology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Prevalence of Free-Living Amoebae in Various Water Sources in Iran: A Systematic Review and Meta-Analysis.Acta parasitologica · 2025Pooled it
- Prevalence of free-living amoebae in swimming pools and recreational waters, a systematic review and meta-analysis.Parasitology research · 2022Pooled it
- Adjunctive povidone-iodine forAntimicrobial agents and chemotherapy · 2026Trial
- Genetic Classification of a Novel Genotype of the GenusTropical medicine and infectious disease · 2026Article
- Article
- Molecular identification of potentially pathogenic free-living amoebae in environmental samples from urban areas of Kerman, Southeastern Iran.Parasite epidemiology and control · 2026Article
- Genetic diversity of Acanthamoeba and clinical outcome predictors in Danish patients with Acanthamoeba keratitis.Acta ophthalmologica · 2026Article
- Molecular and Culture-Based Surveillance of Free-Living Amoebae in Human Related Sources in an Outermost Region.Pathogens (Basel, Switzerland) · 2026Article
- Contamination of medical devices and hospital environments with free-living amoebae: Evidence from hospitals in Northwestern Iran.PloS one · 2026Article
- Review
- High Occurrence of Pathogenic Free-Living Amoebae in Arid Environments.Pathogens (Basel, Switzerland) · 2025Article
- The Microbial Trojan Horse and Antimicrobial Resistance: Acanthamoeba as an Environmental Reservoir for Multidrug Resistant Bacteria.Environmental microbiology · 2025Article
- Microarray-based characterization of airway inflammation induced by environmental Acanthamoeba exposure versus the ovalbumin-alum model.Parasites, hosts and diseases · 2025Article
- Incidence of Acanthamoeba Keratitis in Switzerland.Microorganisms · 2025Article
- Isolation and Molecular Identification of Pathogenic Free-Living Amoebae from Environmental Samples in Tenerife, Canary Islands, Spain.ACS ES&T water · 2025Article
- Assessment of the Presence of Free-Living Amoebae in Soil Samples from the Northwest Region of Spain Using Culture and Molecular Assays.Microorganisms · 2025Article
- Prevalence of free-living amoebae in five rivers associated with high human activity in Tehran province, Iran.Journal of water and health · 2025Article
- Targets for the diagnosis ofmSphere · 2025Article
- Prevalence of HSV Genomic Signatures Among Acanthamoeba Hosts and Contaminated Lens Cases: A Molecular and Clinical Study.Investigative ophthalmology & visual science · 2025Article
- Identification and Characterization of Acanthamoeba from Contact Lens Care Solutions and Hospital Environments in the Ophthalmology Wards and Operating Rooms in Southeastern Iran.Acta parasitologica · 2025Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acanthamoeba spp. are among the most worldwide prevalent protozoa. It is the causative agent of a disease known as Acanthamoeba keratitis, a painful and severe sight-threatening corneal infection that can lead to blindness. In recent years, the prevalence of Acanthamoeba keratitis has rapidly increased, growing its importance to human health. This systematic review aims to assess the distribution of Acanthamoeba sp. genotypes causing keratitis around the world, considering the sample collected type and the used identification method. Most of the cases were found in Asia and Europe. Not surprisingly, the T4 genotype was the most prevalent worldwide, followed by T3, T15, T11, and T5. Furthermore, the T4 genotype contains a higher number of species. Given the differences in pathology, susceptibility to treatment, and clinical outcome between distinct genotypes, it is essential to genotype isolates from Acanthamoeba keratitis cases to help to establish a better correlation between in vitro and in vivo activities, resulting in better drug therapies and successful treatment in cases of this important ocular infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.