ArticleEuropean journal of nutrition2022
Dietary inflammatory index and its relationship with gut microbiota in individuals with intestinal constipation: a cross-sectional study.
Article in European journal of nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- The association of dietary inflammatory index with sleep outcomes: A systematic review.Health promotion perspectives · 2024Pooled it
- The effectiveness of a plant-based milk with fermented brown rice on constipation symptoms via gut microbiota modulation: a double-blind randomized controlled trial.European journal of nutrition · 2026Trial
- Impact of Probiotic Formula (Lacto-5X) on Constipation: Improvements in Gastrointestinal Symptoms, Gut Microbiome, and Metabolites.Journal of microbiology and biotechnology · 2025Trial
- The Impact of Oral-Gut Microbiota Structure and Its Manipulation on RA Development and Management.Food science & nutrition · 2026Review
- Immune-gut-metabolite Interactions in Multiple Sclerosis: A Mendelian Randomization and Mediation Study.Current neurovascular research · 2026Article
- Gestational constipation and the gut microbiota: mechanisms, interventions, and implications for maternal and offspring health.Frontiers in nutrition · 2026Review
- Dietary Patterns and Incident Chronic Constipation in Three Prospective Cohorts of Middle- and Older-Aged Adults.Gastroenterology · 2025Article
- Article
- Assessing the gut microbiota composition in older adults: connections to physical activity and healthy ageing.GeroScience · 2025Observational
- Perinatal depressive and anxiety symptoms are associated with gut microbiota in pregnant women with overweight and obesity.Brain, behavior, & immunity - health · 2025Article
- Article
- Effect of Preoperative Inflammatory Diet on Clinical and Oncologic Outcomes Following Colorectal Cancer Surgery.Nutrients · 2025Article
- Complex Probiotics Ameliorate Fecal Microbiota Transplantation-Induced IBS in Mice via Gut Microbiota and Metabolite Modulation.Nutrients · 2025Article
- Porcine Bile Acids Improve Antioxidant Status and Immune Function by IncreasingAnimals : an open access journal from MDPI · 2025Article
- Association between pro-inflammatory diet and fecal incontinence: a large population-based study.Frontiers in nutrition · 2025Article
- Article
- Associations of MIND and DI-GM dietary scores with depression, anxiety, and gut microbiota in patients with colon cancer: a cross-sectional study.Frontiers in nutrition · 2025Article
- Therapeutic Mechanism of Zhuyang Tongbian Decoction in Treating Functional Constipation: Insights from a Pilot Study Utilizing 16S rRNA Sequencing, Metagenomics, and Metabolomics.International journal of general medicine · 2025Article
- Non-linear relationship between Dietary Inflammatory Index and constipation: threshold identification and insights from NHANES [2005-2010] and Mendelian randomization analysis.Translational gastroenterology and hepatology · 2025Article
- Association between dietary inflammatory index and energy-adjusted dietary inflammatory index and constipation in US adults.BMC gastroenterology · 2024Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine whether there is an association between the inflammatory potential of the diet, measured by the dietary inflammatory index (DII®), and the composition of intestinal microbiota in adults with functional constipation (FC).
methodsA cross-sectional study was carried out with 68 adults with FC. Energy-adjusted DII (E-DII) was calculated from data obtained from food surveys, serum inflammation markers were measured and the composition of the intestinal microbiota was evaluated using the 16S rRNA gene sequencing method. Participants were assigned into two groups: anti-inflammatory diet (AD: E-DII < 0) and pro-inflammatory diet (PD: E-DII ≥ 0). Associations of E-DII scores with microbial diversity and composition were examined using differences between the E-DII groups and linear and hierarchical regression.
resultsE- DII was inversely correlated with relative abundance of Hungatella spp. and Bacteroides fragilis and positively correlated with Bacteroides thetaiotaomicron and Bacteroides caccae (p < 0.05). B. fragilis was positively correlated with IL-10. The AD group had higher relative abundances for the genus Blautia and Hungatella, lower abundances of Bacteroides thetaiotamicron and Bacteroides spp. (p < 0.05), as well as higher frequency of evacuation (p = 0.02) and lower use of laxatives (p = 0.05). The AD group showed a reduction in the abundance of Desulfovibrio spp. and Butyrivibrio, Butyrivibrio crossotus, Bacteroides clarus, Bacteroides coprophilus and Bacteroides intestinalis (all p < 0.05). The greater abundance of Bacteroides clarus increased the individual's chance of performing a manual evacuation maneuver.
conclusionTherefore, the results of this study demonstrated that the inflammatory potential of the diet is associated with the gut microbiota in individuals with FC.
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