Evidence map›Paper›PMID 34351055›Full record

ArticleJournal of applied clinical medical physics2021

Comparison of treatment plans for hypofractionated high-dose prostate cancer radiotherapy using the Varian Halcyon and the Elekta Synergy platforms.

Jörg Tamihardja, Gary Razinskas, Florian Exner, Anne Richter, Patrick Kessler, Stefan Weick, Johannes Kraft, Frederick Mantel, Michael Flentje, Bülent Polat

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Linear accelerator selection: impact on feasibility dose-volume histograms and practicality in dose reduction for organs at risk during prostate volumetric-modulated arc therapy.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jörg TamihardjaDepartment of Radiation Oncology, University of Würzburg, Würzburg, Germany.ORCID https://orcid.org/0000-0002-6995-3956
Gary RazinskasDepartment of Radiation Oncology, University of Würzburg, Würzburg, Germany.
Florian ExnerDepartment of Radiation Oncology, University of Würzburg, Würzburg, Germany.
Anne RichterDepartment of Radiation Oncology, University of Würzburg, Würzburg, Germany.
Patrick KesslerDepartment of Radiation Oncology, University of Würzburg, Würzburg, Germany.
Stefan WeickDepartment of Radiation Oncology, University of Würzburg, Würzburg, Germany.
Johannes KraftDepartment of Radiation Oncology, University of Würzburg, Würzburg, Germany.
Frederick MantelDepartment of Radiation Oncology, University of Würzburg, Würzburg, Germany.
Michael FlentjeDepartment of Radiation Oncology, University of Würzburg, Würzburg, Germany.
Bülent PolatDepartment of Radiation Oncology, University of Würzburg, Würzburg, Germany.
University of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare radiotherapy plans between an O-ring and a conventional C-arm linac for hypofractionated high-dose prostate radiotherapy in terms of plan quality, dose distribution, and quality assurance in a multi-vendor environment.

methodsTwenty prostate cancer treatment plans were irradiated on the O-ring Varian Halcyon linac and were re-optimized for the C-arm Elekta Synergy Agility linac. Dose-volume histogram metrics for target coverage and organ at risk dose, quality assurance, and monitor units were retrospectively compared. Patient-specific quality assurance with ion chamber measurements, gamma index analysis, and portal dosimetry was performed using the Varian Portal Dosimetry system and the ArcCHECK

resultsFor both linacs, target coverage was excellent and plan quality comparable. Homogeneity in PTV

conclusionHypofractionated high-dose prostate cancer SIB VMAT on the Halcyon system is feasible with comparable plan quality in reference to a standard C-arm Elekta Synergy linac.

Indexed as

Prostatic NeoplasmsRadiotherapy, Intensity-ModulatedHumansMaleRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRetrospective Studiesacute toxicitydose evaluationHalcyonhypofractionationprostate cancerSynergy

Identifiers

PMID34351055
PMCPMC8425948
OpenAlexW3188277285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.