Evidence map›Paper›PMID 34351018›Full record

ArticleJournal of veterinary internal medicine2021

Gastric microbiome in horses with and without equine glandular gastric disease.

Linda J Paul, Aaron C Ericsson, Frank M Andrews, Michael L Keowen, Francisco Morales Yniguez, Frank Garza, Heidi E Banse

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
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  8. Article
  9. Equine Gastric Ulcer Syndrome: An Update on Current Knowledge.Animals : an open access journal from MDPI · 2023
    Review
  10. Article
  11. Review
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Linda J PaulLouisiana State University, Veterinary Clinical Sciences, Equine Health Studies Program, Baton Rouge, Louisiana, USA.ORCID https://orcid.org/0000-0002-1298-5615
Aaron C EricssonMetagenomics Center, Equine Gut Group, University of Missouri, Columbia, Missouri, USA.
Frank M AndrewsLouisiana State University, Veterinary Clinical Sciences, Equine Health Studies Program, Baton Rouge, Louisiana, USA.ORCID https://orcid.org/0000-0001-7930-6237
Michael L KeowenLouisiana State University, Veterinary Clinical Sciences, Equine Health Studies Program, Baton Rouge, Louisiana, USA.
Francisco Morales YniguezLouisiana State University, Veterinary Clinical Sciences, Equine Health Studies Program, Baton Rouge, Louisiana, USA.
Frank GarzaLouisiana State University, Veterinary Clinical Sciences, Equine Health Studies Program, Baton Rouge, Louisiana, USA.
Heidi E BanseLouisiana State University, Veterinary Clinical Sciences, Equine Health Studies Program, Baton Rouge, Louisiana, USA.
Louisiana State University · USUniversity of Missouri · US

Funding

LSU Equine Health Studies Program Charles V. Cusimano Grant
6 · The paper itself

Abstract

backgroundThe role of the gastric microbiome in development or persistence of equine glandular gastric disease (EGGD) remains to be investigated. HYPOTHESIS/

objectivesThe objective was to characterize the glandular mucosal and gastric fluid microbiomes of horses with and without EGGD. It was hypothesized that differences in the mucosal microbiome are associated with EGGD. ANIMALS: Twenty-four horses were enrolled.

methodsGastroscopy was performed and EGGD scores recorded (score 0, n = 6; score 1, n = 8; score ≥2, n = 10). Gastric fluid and pinch biopsies of healthy glandular mucosa and EGGD lesions were collected via gastroscope. 16S rRNA amplicon sequencing of the gastric fluid and glandular mucosal biopsies was performed. Relationships between gastric fluid and mucosal microbial community composition were evaluated among EGGD score groups (EGGD 0-BX, EGGD 1-BX, EGGD ≥2-BX) and among endoscopic appearances: controls from horses without EGGD and normal areas, hyperemic areas, and lesions from horses with EGGD.

resultsMicrobial community structure of mucosal biopsies differed among EGGD score groups (Jaccard similarity index; P = .009). Principal coordinate analysis showed separate clusters for EGGD 0-BX and EGGD ≥2-BX. CONCLUSIONS AND CLINICAL IMPORTANCE: A modest difference was detected in the community structure of the gastric glandular mucosal microbiome in association with EGGD score.

Indexed as

Gastrointestinal MicrobiomeHorse DiseasesStomach DiseasesStomach UlcerAnimalsGastric MucosaHorsesRNA, Ribosomal, 16SRNA, Ribosomal, 16Sbioinformaticscolicequine gastric ulcer syndrome (EGUS)stomach

Identifiers

PMID34351018
PMCPMC8478018
OpenAlexW3191005923

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.