Evidence map›Paper›PMID 34350489›Full record

ArticleWorld journal of surgery2021

Enhanced Recovery After Surgery Protocol Minimizes Intensive Care Unit Utilization and Improves Outcomes Following Pulmonary Resection.

Terrance Peng, Kimberly A Shemanski, Li Ding, Elizabeth A David, Anthony W Kim, Michael Kim, Dustin K Lieu, Sean C Wightman, Jasmine Zhao, Scott M Atay

Abstract read
In one paragraph

Article in World journal of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  4. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Terrance Peng *Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA. terrance.peng@usc.edu.
Kimberly A Shemanski *Department of Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Li DingDepartment of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Elizabeth A DavidDepartment of Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Anthony W KimDepartment of Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Michael KimDepartment of Anesthesia, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Dustin K LieuKeck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Sean C WightmanDepartment of Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Jasmine ZhaoKeck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Scott M AtayDepartment of Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.

Funding

Southern California Clinical and Translational Science InstituteUL1TR001855 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Thomas A Buchanan, Michele D. Kipke · 2016 to 2026
$81.3M
Southern California Clinical and Translational Science InstituteUL1TR000130 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BUCHANAN, THOMAS A · 2012 to 2015
$36.0M
NCATS NIH HHS UL1 TR000130NCATS NIH HHS UL1 TR001855
6 · The paper itself

Abstract

backgroundEnhanced recovery after surgery (ERAS) protocols have been associated with improved postoperative outcomes but require further validation in thoracic surgery. This study evaluated outcomes of patients undergoing pulmonary resection before and after implementation of an ERAS protocol.

methodsElectronic medical records were queried for all patients undergoing pulmonary resection between April 2017 and April 2019. Patients were grouped into pre- and post-ERAS cohorts based on dates of operation. The ERAS protocol prioritized early mobilization, limited invasive monitoring, euvolemia, and non-narcotic analgesia. Primary outcome measures included intensive care unit (ICU) utilization, postoperative pain metrics, and perioperative morbidity. Regression analyses were performed to identify predictors of morbidity. Subgroup analyses were performed by pulmonary risk profile and surgical approach.

resultsA total of 64 pre- and 67 post-ERAS patients were included in the study. ERAS implementation was associated with reduced postoperative ICU admission (pre: 65.6% vs. post: 19.4%, p < 0.0001), shorter ICU median length of stay (LOS) (pre: 1 vs. post: 0, p < 0.0001), and decreased opioid usage measured by median morphine milligram equivalents (pre: 40.5 vs. post: 20.0, p < 0.0001). Post-ERAS patients also reported lower visual analog scale (VAS) pain scores on postoperative days (POD) 1 and 2 (pre: 6.3/5.6 vs. post: 5.3/4.2, p = 0.04/0.01) as well as average VAS pain score over POD0-2 (pre: 6.2 vs. post: 5.2, p = 0.005).

conclusionsImplementation of an ERAS protocol for pulmonary resection, which dictated reduced ICU admissions, did not increase major postoperative morbidity. Additionally, ERAS-enrolled patients reported improved postoperative pain control despite decreased opioid utilization.

Indexed as

Enhanced Recovery After SurgeryAnalgesics, OpioidHumansIntensive Care UnitsLength of StayPostoperative ComplicationsPostoperative PainRetrospective StudiesAnalgesics, Opioid

Identifiers

PMID34350489
PMCPMC8336670

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.