Evidence map›Paper›PMID 34350401›Full record

ArticleNeuroscience insights2021

Alzheimer's and Consciousness: How Much Subjectivity Is Objective?

Vladan Bajic, Natasa Misic, Ivana Stankovic, Bozidarka Zaric, George Perry

Abstract read
In one paragraph

Article in Neuroscience insights, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vladan BajicDepartment of Radiobiology and Molecular Genetics, Vinca Institute, University of Belgrade, Belgrade, Serbia.
Natasa MisicLola Institute, Belgrade, Serbia.
Ivana StankovicInstitute of Chemistry, Technology and Metallurgy, University of Belgrade, Belgrade, Serbia.
Bozidarka ZaricDepartment of Radiobiology and Molecular Genetics, Vinca Institute, University of Belgrade, Belgrade, Serbia.ORCID https://orcid.org/0000-0003-4244-3283
George PerryDepartment of Biology, The University of Texas at San Antonio, San Antonio, TX, USA.ORCID https://orcid.org/0000-0002-6547-0172

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Does Alzheimer Disease show a decline in cognitive functions that relate to the awareness of external reality? In this paper, we will propose a perspective that patients with increasing symptoms of AD show a change in the awareness of subjective versus objective representative axis of reality thus consequently move to a more internal like perception of reality. This paradigm shift suggests that new insights into the dynamicity of the conscious representation of reality in the AD brain may give us new clues to the very early signs of memory and self-awareness impairment that originates from, in our view the microtubules. Dialog between Adso and William, in Umberto Eco's The Name of the Rose, Third Day: Vespers. "But how does it happen," I said with admiration, "that you were able to solve the mystery of the library looking at it from the outside, and you were unable to solve it when you were inside?" "Thus, God knows the world, because He conceived it in His mind, as if it was from the outside, before it was created, and we do not know its rule, because we live inside it, having found it already made."

Indexed as

Alzheimer diseaseconsciousnessdynamicitymicrotubulesobjectivityself-awarenesssubjectivity

Identifiers

PMID34350401
PMCPMC8295942

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.