Evidence map›Paper›PMID 34350397›Full record

ArticleTherapeutic advances in gastrointestinal endoscopy

Multichannel impedance monitoring for distinguishing nonerosive reflux esophagitis with minor changes on endoscopy in children.

Fujino Junko, David Moore, Taher Omari, Grace Seiboth, Rammy Abu-Assi, Paul Hammond, Richard Couper

Open access · goldAbstract read
In one paragraph

Article in Therapeutic advances in gastrointestinal endoscopy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Fujino JunkoSaitama Medical Center, Dokkyo Medical University, 2-1-50 Minamikoshigaya, Koshigaya-shi, Saitama 343-8555, Japan.ORCID https://orcid.org/0000-0003-0440-6502
David MooreGastroenterology Unit, Women's and Children's Hospital, North Adelaide, SA, Australia.
Taher OmariSchool of Medicine, Flinders University, Adelaide, SA, Australia.
Grace SeibothGastroenterology Unit, Women's and Children's Hospital, North Adelaide, SA, Australia.
Rammy Abu-AssiGastroenterology Unit, Women's and Children's Hospital, North Adelaide, SA, Australia.
Paul HammondGastroenterology Unit, Women's and Children's Hospital, North Adelaide, SA, Australia.
Richard CouperGastroenterology Unit, Women's and Children's Hospital, North Adelaide, SA, Australia.
Women's and Children's Hospital · AUDokkyo Medical University Saitama Medical Center · JPFlinders University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThere are reports describing the relationship between baseline impedance level and esophageal mucosal integrity at endoscopy, such as erosive and nonerosive reflux esophagitis. However, many children with symptoms of gastroesophageal reflux disease have normal findings or minor changes on esophagogastroduodenoscopy. We aimed to examine whether modest changes at esophagogastroduodenoscopy can be evaluated and correlated with esophageal multichannel intraluminal impedance monitoring.

methodsPatients (ages 0-17 years) with upper gastrointestinal symptoms who underwent combined esophagogastroduodenoscopy and multichannel intraluminal impedance monitoring at the Women's and Children's Hospital, Adelaide, Australia, between 2014 and 2016 were retrospectively studied and the following data were collected and used for analysis: demographics, multichannel intraluminal impedance data, included baseline impedance. Endoscopic findings were classified by modified Los Angeles grading, Los Angeles

resultsSeventy patients (43 boys; 61%) were enrolled with a mean age of 7.9 years (range 10 months to 17 years). Fifty-one patients (72.9%) were allocated to Los Angeles

conclusionLower baseline impedance is helpful in predicting minimal endoscopic changes in the lower esophagus. A higher frequency of acid and nonacid reflux episodes was also predictive of minimal endoscopic change in the lower esophagus.

Indexed as

childrenminimal changenonerosive esophagitisreflux esophagitis

Identifiers

PMID34350397
PMCPMC8287343
OpenAlexW3163306311

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.