Evidence map›Paper›PMID 34350388›Full record

ArticleJAMIA open2021

FIBER: enabling flexible retrieval of electronic health records data for clinical predictive modeling.

Suparno Datta, Jan Philipp Sachs, Harry FreitasDa Cruz, Tom Martensen, Philipp Bode, Ariane Morassi Sasso, Benjamin S Glicksberg, Erwin Böttinger

Abstract read
In one paragraph

Article in JAMIA open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Suparno DattaDigital Health Center, Hasso Plattner Institute, University of Potsdam, Potsdam, Germany.ORCID https://orcid.org/0000-0002-2714-3250
Jan Philipp SachsDigital Health Center, Hasso Plattner Institute, University of Potsdam, Potsdam, Germany.
Harry FreitasDa CruzDigital Health Center, Hasso Plattner Institute, University of Potsdam, Potsdam, Germany.
Tom MartensenDigital Health Center, Hasso Plattner Institute, University of Potsdam, Potsdam, Germany.
Philipp BodeDigital Health Center, Hasso Plattner Institute, University of Potsdam, Potsdam, Germany.
Ariane Morassi SassoDigital Health Center, Hasso Plattner Institute, University of Potsdam, Potsdam, Germany.
Benjamin S GlicksbergHasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Erwin BöttingerDigital Health Center, Hasso Plattner Institute, University of Potsdam, Potsdam, Germany.

Funding

Big Omics Data Engine 2 SupercomputerS10OD026880 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2019 to 2019
$2.0M
NIH HHS S10 OD026880
6 · The paper itself

Abstract

objectivesThe development of clinical predictive models hinges upon the availability of comprehensive clinical data. Tapping into such resources requires considerable effort from clinicians, data scientists, and engineers. Specifically, these efforts are focused on data extraction and preprocessing steps required prior to modeling, including complex database queries. A handful of software libraries exist that can reduce this complexity by building upon data standards. However, a gap remains concerning electronic health records (EHRs) stored in star schema clinical data warehouses, an approach often adopted in practice. In this article, we introduce the FlexIBle EHR Retrieval (FIBER) tool: a Python library built on top of a star schema (i2b2) clinical data warehouse that enables flexible generation of modeling-ready cohorts as data frames. MATERIALS AND

methodsFIBER was developed on top of a large-scale star schema EHR database which contains data from 8 million patients and over 120 million encounters. To illustrate FIBER's capabilities, we present its application by building a heart surgery patient cohort with subsequent prediction of acute kidney injury (AKI) with various machine learning models.

resultsUsing FIBER, we were able to build the heart surgery cohort (

conclusionFIBER is an open-source Python library developed for extracting information from star schema clinical data warehouses and reduces time-to-modeling, helping to streamline the clinical modeling process.

Indexed as

databaseselectronic health recordsfactualinformation storage and retrievalsoftware/instrumentationworkflow

Identifiers

PMID34350388
PMCPMC8327378

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.