ArticleRheumatology advances in practice2021
Reduced cognitive ability in people with rheumatoid arthritis compared with age-matched healthy controls.
Article in Rheumatology advances in practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Exploring Factors Associated With Cognitive Impairment in Rheumatoid Arthritis.Arthritis care & research · 2026Article
- Dynamic psychological vulnerability and adaptation in rheumatoid arthritis: Trajectories, predictors, and interventions.World journal of psychiatry · 2026Review
- Economic and Humanistic Burden of Rheumatoid Arthritis: Results From the US National Survey Data 2018-2020.ACR open rheumatology · 2024Article
- Executive Functions and Public Health: A Narrative Review.Iranian journal of public health · 2023Review
- Utility of Chinese Versions of Addenbrooke's Cognitive Examination: A Narrative Review.Healthcare (Basel, Switzerland) · 2022Review
- Does culture shape our understanding of others' thoughts and emotions? An investigation across 12 countries.Neuropsychology · 2022Article
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Authors and funding
9 authors.
Funding
Abstract
objectiveThe aim was to compare the cognitive ability of people with RA with healthy controls (HCs).
methodsPeople with RA were recruited from the Norfolk Arthritis Register (NOAR), a population-based cohort study of people with inflammatory arthritis. Data on aged-matched HCs (people with no cognitive impairment) came from the comparison arm of The Dementia Research and Care Clinic Study (TRACC). People with RA and HCs performed a range of cognitive ability tasks to assess attention, memory, verbal fluency, language, visuospatial skills, emotional recognition, executive function and theory of mind. A score of <88 on the Addenbrooke's Cognitive Examination III was considered cognitive impairment. Scores were compared using linear regression adjusting for age, sex, smoking status, education, BMI, anxiety and depression.
resultsThirty-eight people with RA [mean (S.D.) age: 69.1 (8.0) years; 25 (65.8%) women] were matched with 28 HCs [mean (S.D.) age: 68.2 (6.4) years; 15 (53.6%) women]. Twenty-three (60.5%) people with RA were considered to have mild cognitive impairment [mean (S.D.) Addenbrooke's Cognitive Examination III: RA = 85.2 (7.4), HC = 96.0 (2.5)]. People with RA had impairments in memory, verbal fluency, visuospatial functioning, executive function and emotional recognition in faces compared with HCs, after adjustment for confounders.
conclusionPeople with RA had cognitive impairments in a range of domains. People with RA might benefit from cognitive impairment screening to allow for early administration of appropriate interventions.
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