Evidence map›Paper›PMID 34350342›Full record

ArticleAPL photonics2020

Super-resolution localization microscopy: Toward high throughput, high quality, and low cost.

Hongqiang Ma, Yang Liu

Abstract read
In one paragraph

Article in APL photonics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  5. Review
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  13. Probing Chromatin Compaction and Its Epigenetic StatesFrontiers in cell and developmental biology · 2021
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hongqiang MaBiomedical Optical Imaging Laboratory, Departments of Medicine and Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.ORCID 0000-0003-1967-3777
Yang LiuBiomedical Optical Imaging Laboratory, Departments of Medicine and Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.ORCID 0000-0002-6388-9674

Funding

(PQC2)Nanoscale changes in 3D nuclear architecture during breast tumorigenesisR01CA185363 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LIU, YANG · 2014 to 2017
$1.3M
High-throughput super-resolution imaging of chromatin structures at different epigenetic statesR33CA225494 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LIU, YANG · 2018 to 2020
$1.1M
NCI NIH HHS R01 CA185363NCI NIH HHS R33 CA225494
6 · The paper itself

Abstract

After nearly 15 years since its initial debut, super-resolution localization microscopy that surpasses the diffraction-limited resolution barrier of optical microscopy has rapidly gotten out of the ivory tower and entered a new phase to address various challenging biomedical questions. Recent advances in this technology greatly increased the imaging throughput, improved the imaging quality, simplified the sample preparation, and reduced the system cost, making this technology suitable for routine biomedical research. We will provide our perspective on the recent technical advances and their implications in serving the community of biomedical research.

Identifiers

PMID34350342
PMCPMC8330581

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.