Evidence map›Paper›PMID 34350282›Full record

ArticleERJ open research2021

Compatibility of a novel filter paper-based bio-safe sputum transport kit with line probe assay for diagnosing drug-resistant tuberculosis: a single-site evaluation study.

Divya Anthwal, Rakesh Kumar Gupta, Ritu Singhal, Manpreet Bhalla, Ajoy Kumar Verma, Khalid Umar Khayyam, Vithal Prasad Myneedu, Rohit Sarin, Ashawant Gupta, Nalini Kant Gupta and 3 more

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Development and evaluation of 'Quick TB DNA Extraction' kit for the rapid and efficient detection of multidrug-resistant tuberculosis from sputum transported on bio-safe filter.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Divya AnthwalDept of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Rakesh Kumar GuptaDept of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Ritu SinghalDept of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India.
Manpreet BhallaDept of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India.
Ajoy Kumar VermaDept of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India.
Khalid Umar KhayyamDept of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India.
Vithal Prasad MyneeduDept of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India.
Rohit SarinDept of Microbiology, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, India.
Ashawant GuptaAdvanced Microdevices Pvt Ltd, Ambala Cantt, India.
Nalini Kant GuptaAdvanced Microdevices Pvt Ltd, Ambala Cantt, India.
Manjula SinghIndia TB Research Consortium, Indian Council of Medical Research, New Delhi, India.
Jaya Sivaswami TyagiTranslational Health Science and Technology Institute, NCR Biotech Science Cluster, Faridabad, India.ORCID https://orcid.org/0000-0002-6052-1137
Sagarika HaldarDept of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.ORCID https://orcid.org/0000-0001-8276-4458
LRS Institute of Tuberculosis and Respiratory Diseases · INTranslational Health Science and Technology Institute · INIndian Council of Medical Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNear-patient access to appropriate tests is a major obstacle for the efficient diagnosis of tuberculosis (TB) and associated drug resistance.

methodsWe recently developed the "TB Concentration & Transport" kit for bio-safe, ambient-temperature transportation of dried sputum on

results

conclusionsThis study demonstrates successful integration of our developed kits with LPA. The adoption of these kits across Designated Microscopy Centres in India can potentially overcome the existing challenge of transporting infectious sputum at controlled temperature to centralised testing laboratories and can provide rapid near-patient cost-effective "Universal DST" services to TB subjects residing in remote areas.

Identifiers

PMID34350282
PMCPMC8326685
OpenAlexW3160395337

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.