Evidence map›Paper›PMID 34350188›Full record

ReviewFrontiers in cell and developmental biology2021

Using

Sara A Kirolos, Ramesh Rijal, Kristen M Consalvo, Richard H Gomer

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Cell biology of Dictyostelium.BMC molecular and cell biology · 2025
    Article
  5. Two endogenousProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Review
  7. Mfsd8 Modulates Growth and the Early Stages of Multicellular Development inFrontiers in cell and developmental biology · 2022
    Article
  8. Identification of novel proteins in themicroPublication biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sara A KirolosDepartment of Biology, Texas A&M University, College Station, TX, United States.
Ramesh RijalDepartment of Biology, Texas A&M University, College Station, TX, United States.
Kristen M ConsalvoDepartment of Biology, Texas A&M University, College Station, TX, United States.
Richard H GomerDepartment of Biology, Texas A&M University, College Station, TX, United States.
Texas A&M University · US

Funding

Elucidation of a Eukaryotic Chemorepulsion MechanismR35GM139486 · NIGMS · TEXAS A&M UNIVERSITY · PI Richard H Gomer · 2021 to 2026
$2.3M
Elucidation of a eukaryotic chemorepulsion mechanismR01GM118355 · NIGMS · TEXAS A&M UNIVERSITY · PI GOMER, RICHARD H · 2016 to 2019
$1.2M
NIGMS NIH HHS R01 GM118355NIGMS NIH HHS R35 GM139486
6 · The paper itself

Abstract

Acute respiratory distress syndrome (ARDS) involves damage to lungs causing an influx of neutrophils from the blood into the lung airspaces, and the neutrophils causing further damage, which attracts more neutrophils in a vicious cycle. There are ∼190,000 cases of ARDS per year in the US, and because of the lack of therapeutics, the mortality rate is ∼40%. Repelling neutrophils out of the lung airspaces, or simply preventing neutrophil entry, is a potential therapeutic. In this minireview, we discuss how our lab noticed that a protein called AprA secreted by growing

Indexed as

acute respiratory disease syndromechemorepulsionDictyostelium discoideumDPPIVneutrophil (PMN)PAR2

Identifiers

PMID34350188
PMCPMC8326840
OpenAlexW3186666593

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.