Evidence map›Paper›PMID 34350134›Full record

ArticleFrontiers in cellular and infection microbiology2021

Biological Effect of

Kazunori Murase, Chihiro Aikawa, Takashi Nozawa, Ayako Nakatake, Kuniyo Sakamoto, Taisei Kikuchi, Ichiro Nakagawa

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. iScience · 2025
    Article
  5. Article
  6. Journal of oral microbiology · 2025
    Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. International journal of molecular sciences · 2022
    Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kazunori MuraseDepartment of Microbiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Chihiro AikawaDepartment of Microbiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Takashi NozawaDepartment of Microbiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ayako NakatakeHTLV-1/ATL Research Facility, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.
Kuniyo SakamotoHTLV-1/ATL Research Facility, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.
Taisei KikuchiDepartment of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.
Ichiro NakagawaDepartment of Microbiology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kyoto University · JPUniversity of Miyazaki · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most bacteria naturally release spherical lipid-bilayered extracellular vesicles (EVs) containing proteins, nucleic acids, and virulence-related molecules, thus contributing to diverse biological functions including transport of virulence factors. The group A streptococcus,

Indexed as

Extracellular VesiclesStreptococcus pyogenesBacterial ProteinsHumansInflammationMonocytesNAD+ NucleosidaseVirulenceVirulence FactorsBacterial ProteinsNAD+ NucleosidaseVirulence Factorscytotoxicityextracellular vesiclesinflammatory responsepathogenicityStreptococcus pyogenes

Identifiers

PMID34350134
PMCPMC8326760
OpenAlexW3186077765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.