Evidence map›Paper›PMID 34350132›Full record

ArticleFrontiers in cellular and infection microbiology2021

Helminth Coinfection Is Associated With Enhanced Plasma Levels of Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinases in Tuberculous Lymphadenitis.

Gokul Raj Kathamuthu, Kadar Moideen, Kannan Thiruvengadam, Rathinam Sridhar, Dhanaraj Baskaran, Subash Babu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Frontiers in immunology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Gokul Raj KathamuthuNational Institutes of Health-NIRT-International Center for Excellence in Research, Chennai, India.
Kadar MoideenNational Institutes of Health-NIRT-International Center for Excellence in Research, Chennai, India.
Kannan ThiruvengadamNational Institute for Research in Tuberculosis (NIRT), Chennai, India.
Rathinam SridharGovernment Stanley Medical Hospital, Chennai, India.
Dhanaraj BaskaranNational Institute for Research in Tuberculosis (NIRT), Chennai, India.
Subash BabuNational Institutes of Health-NIRT-International Center for Excellence in Research, Chennai, India.
International Centers for Excellence in Research · INNational Institute of Research in Tuberculosis · INStanley Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Matrix metalloproteinases (MMPs) are crucial for tissue remodeling and repair and are expressed in diverse infections, whereas tissue inhibitors of metalloproteinases (TIMPs) are endogenous inhibitors of MMPs. However, the interaction of MMPs and TIMPs in tuberculous lymphadenitis (TBL), an extra-pulmonary form of tuberculosis (EPTB) and helminth (Hel+) coinfection is not known. Therefore, this present study investigates the levels of circulating MMPs (1, 2, 3, 7, 8, 9, 12, 13) and TIMPs (1, 2, 3, 4) in TBL individuals with helminth (

Indexed as

CoinfectionHelminthiasisTuberculosis, Lymph NodeAnimalsHelminthsHumansMatrix MetalloproteinasesTissue Inhibitor of MetalloproteinasesMatrix MetalloproteinasesTissue Inhibitor of Metalloproteinasesextra-pulmonary TBhelminth infectionLuminex ELISAmatrix metalloproteinasestissue inhibitors of metalloproteinases

Identifiers

PMID34350132
PMCPMC8326810
OpenAlexW3186742733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.