Evidence map›Paper›PMID 34350027›Full record

ArticleMultiple sclerosis journal - experimental, translational and clinical

Preliminary testing of a patient decision aid for patients with relapsing-remitting multiple sclerosis.

Nick Bansback, Judy A Chiu, Rebecca Metcalfe, Emmanuelle Lapointe, Alice Schabas, Marilyn Lenzen, Anthony Traboulsee, Larry D Lynd, Robert Carruthers

Abstract read
In one paragraph

Article in Multiple sclerosis journal - experimental, translational and clinical. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. 'So Let's Go On Like This?'-Shared Decision-Making and the Use of Outcome Information in Routine Care Management for People With Multiple Sclerosis.Health expectations : an international journal of public participation in health care and health policy · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nick BansbackSchool of Population and Public Health, University of British Columbia, Vancouver, Canada.
Judy A ChiuCentre for Health Evaluation & Outcome Sciences, St. Paul's Hospital, Vancouver, Canada.
Rebecca MetcalfeSchool of Population and Public Health, University of British Columbia, Vancouver, Canada.
Emmanuelle LapointeDivision of Neurology, University of British Columbia, Vancouver, Canada.ORCID https://orcid.org/0000-0002-8732-1872
Alice SchabasDivision of Neurology, University of British Columbia, Vancouver, Canada.ORCID https://orcid.org/0000-0002-5925-1715
Marilyn LenzenPatient Partner.
Anthony TraboulseeDivision of Neurology, University of British Columbia, Vancouver, Canada.
Larry D LyndFaculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada.
Robert CarruthersDivision of Neurology, University of British Columbia, Vancouver, Canada.ORCID https://orcid.org/0000-0001-7085-1001

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultiple first-line disease modifying therapies (DMTs) are available for relapsing-remitting multiple sclerosis (RRMS), each with different characteristics. We developed an interactive patient decision aid (PtDA) to promote informed shared decision-making (SDM).

objectiveTo test the preliminary effectiveness of the PtDA in participants with RRMS.

methodsKnowledge, and decisional conflict were measured pre- and post- implementation of the PtDA, SDM after the consultation, and 6-month treatment patterns were observed. Differences in scores were analyzed using descriptive statistics and paired t-tests. Qualitative interviews with patients and neurologists were analyzed using thematic analysis.

results52 participants were recruited: most were female (81%), 40 years of age or younger (62%), and had experienced MS for less than 5 years (56%). After participants used the PtDA, there was a significant improvement in decisional conflict (change = 1.00;

conclusionThis pilot study suggests that PtDA use helps RRMS patients and their clinician select a DMT. Future studies will assess the feasibility of implementation and the impact of the PtDA on timely DMT initiation and longer-term adherence.

Indexed as

decision aiddecision-makingdisease-modifying therapiesMultiple sclerosisrelapsing-remittingtreatment

Identifiers

PMID34350027
PMCPMC8287362

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.