Evidence map›Paper›PMID 34349967›Full record

ArticleChemical science2021

Chemically fueled materials with a self-immolative mechanism: transient materials with a fast on/off response.

Patrick S Schwarz, Laura Tebcharani, Julian E Heger, Peter Müller-Buschbaum, Job Boekhoven

Abstract read
In one paragraph

Article in Chemical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. ATP-Regulated Formation of Transient Peptide Amphiphiles Superstructures.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  3. Chemically Driven Division of Protocells by Membrane Budding.Journal of the American Chemical Society · 2024
    Article
  4. Review
  5. Article
  6. Chemically Fueled Supramolecular Materials.Accounts of materials research · 2023
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Patrick S SchwarzDepartment of Chemistry, Technical University of Munich Lichtenbergstraße 4 85748 Garching Germany job.boekhoven@tum.de.
Laura TebcharaniDepartment of Chemistry, Technical University of Munich Lichtenbergstraße 4 85748 Garching Germany job.boekhoven@tum.de.
Julian E HegerLehrstuhl für Funktionelle Materialien, Physik Department, Technische Universität München James-Franck-Str. 1 85748 Garching Germany.ORCID https://orcid.org/0000-0001-7719-0111
Peter Müller-BuschbaumLehrstuhl für Funktionelle Materialien, Physik Department, Technische Universität München James-Franck-Str. 1 85748 Garching Germany.ORCID https://orcid.org/0000-0002-9566-6088
Job BoekhovenDepartment of Chemistry, Technical University of Munich Lichtenbergstraße 4 85748 Garching Germany job.boekhoven@tum.de.ORCID https://orcid.org/0000-0002-9126-2430

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is an increasing demand for transient materials with a predefined lifetime like self-erasing temporary electronic circuits or transient biomedical implants. Chemically fueled materials are an example of such materials; they emerge in response to chemical fuel, and autonomously decay as they deplete it. However, these materials suffer from a slow, typically first order decay profile. That means that over the course of the material's lifetime, its properties continuously change until it is fully decayed. Materials that have a sharp on-off response are self-immolative ones. These degrade rapidly after an external trigger through a self-amplifying decay mechanism. However, self-immolative materials are not autonomous; they require a trigger. We introduce here materials with the best of both,

Identifiers

PMID34349967
PMCPMC8317627

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.