Evidence map›Paper›PMID 34349822›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

Phytochemical Analysis and Investigation of the Antimicrobial and Cytotoxic Activities of

Dorine Nyak Matara, Joseph Mwanzia Nguta, Fredrick Mutie Musila, Isaac Mapenay

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. In-Vivo Anti-Malarial Activity of 80% Methanol Leaf Extract ofJournal of experimental pharmacology · 2024
    Article
  3. Article
  4. Evaluation of Antimicrobial Activity, Cytotoxicity, and Phytochemical Composition ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Dorine Nyak MataraDepartment of Public Health, Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Nairobi, Nairobi, Kenya.ORCID https://orcid.org/0000-0002-4240-0681
Joseph Mwanzia NgutaDepartment of Public Health, Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Nairobi, Nairobi, Kenya.ORCID https://orcid.org/0000-0002-4591-9999
Fredrick Mutie MusilaDepartment of Applied and Technical Biology, School of Biological and Life Sciences, Technical University of Kenya, Nairobi, Kenya.ORCID https://orcid.org/0000-0002-6219-8150
Isaac MapenayDepartment of Public Health, Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Nairobi, Nairobi, Kenya.
University of Nairobi · KETechnical University of Kenya · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncreasing antimicrobial resistance has led to an arduous search for new potent drugs from nature. In this search, plants have proved to be rich reservoirs of efficacious medicinal components that manage ailments. The current study is designed to investigate the phytochemical composition, antimicrobial activity, and the cytotoxicity of the crude root extracts of

methodsThe roots of

resultsThe phytochemical screening indicated the presence of terpenoids, flavonoids, tannins, phenols, polyuronides, saponins, and anthracenes. The brine shrimp lethality assay indicated that all the extracts were highly cytotoxic with LC

conclusionIn this research work, we report that

Identifiers

PMID34349822
PMCPMC8328688
OpenAlexW3183941956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.