Evidence map›Paper›PMID 34349610›Full record

ArticleMediators of inflammation2021

Astaxanthin Inhibits Interleukin-6 Expression in Cerulein/Resistin-Stimulated Pancreatic Acinar Cells.

Min Seung Kwak, Joo Weon Lim, Hyeyoung Kim

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Min Seung KwakDepartment of Food and Nutrition, BK 21 FOUR, College of Human Ecology, Yonsei University, Seoul 03722, Republic of Korea.ORCID https://orcid.org/0000-0001-8330-957X
Joo Weon LimDepartment of Food and Nutrition, BK 21 FOUR, College of Human Ecology, Yonsei University, Seoul 03722, Republic of Korea.ORCID https://orcid.org/0000-0001-7483-3820
Hyeyoung KimDepartment of Food and Nutrition, BK 21 FOUR, College of Human Ecology, Yonsei University, Seoul 03722, Republic of Korea.ORCID https://orcid.org/0000-0002-7019-917X
Yonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute pancreatitis is a common clinical condition with increasing the proinflammatory mediators, including interleukin-6 (IL-6). Obesity is a negative prognostic factor in acute pancreatitis. Obese patients with acute pancreatitis have a higher systemic inflammatory response rate. Levels of serum resistin, an adipocytokine secreted by fat tissues, increase with obesity. Cerulein, a cholecystokinin analog, induces calcium (Ca

Indexed as

Acinar CellsAdipokinesAnimalsAnti-Inflammatory AgentsCalciumCell LineCeruletideChelating AgentsInterleukin-6NADPH OxidasesObesityOxidative StressPancreasRatsReactive Oxygen SpeciesResistinAdipokinesAnti-Inflammatory AgentsastaxanthineCalciumCeruletideChelating AgentsIl6 protein, ratInterleukin-6NADPH OxidasesReactive Oxygen SpeciesResistinXanthophylls

Identifiers

PMID34349610
PMCPMC8328718
OpenAlexW3185707803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.