Evidence map›Paper›PMID 34349576›Full record

ArticleRisk management and healthcare policy2021

Machine Learning Algorithms are Superior to Conventional Regression Models in Predicting Risk Stratification of COVID-19 Patients.

Jiru Ye, Meng Hua, Feng Zhu

Abstract read
In one paragraph

Article in Risk management and healthcare policy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
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10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Predicting health-related quality of life two years post-diagnosis across seven cancer types: using machine learning to identify vulnerable patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  2. Article
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  4. How Will AI Shape the Future of Pandemic Response? Early Clues From Data Analytics.Risk analysis : an official publication of the Society for Risk Analysis · 2025
    Review
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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Jiru YeDepartment of Respiratory and Critical Care Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, 213003, China.
Meng HuaDepartment of Respiratory and Critical Care Medicine, Wuxi Fifth People's Hospital, Wuxi, 214000, China.
Feng ZhuDepartment of Respiratory and Critical Care Medicine, Wuxi Fifth People's Hospital, Wuxi, 214000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is very important to determine the risk of patients developing severe or critical COVID-19, but most of the existing risk prediction models are established using conventional regression models. We aim to use machine learning algorithms to develop predictive models and compare predictive performance with logistic regression models.

methodsThe medical record of 161 COVID-19 patients who were diagnosed January-April 2020 were retrospectively analyzed. The patients were divided into two groups: asymptomatic-moderate group (132 cases) and severe or above group (29 cases). The clinical features and laboratory biomarkers of these two groups were compared. Machine learning algorithms and multivariate logistic regression analysis were used to construct two COVID-19 risk stratification prediction models, and the area under the curve (AUC) was used to compare the predictive efficacy of these two models.

resultsA machine learning model was constructed based on seven characteristic variables: high sensitivity C-reactive protein (hs-CRP), procalcitonin (PCT), age, neutrophil count (Neuc), hemoglobin (HGB), percentage of neutrophils (Neur), and platelet distribution width (PDW). The AUC of the model was 0.978 (95% CI: 0.960-0.996), which was significantly higher than that of the logistic regression model (0.827; 95% CI: 0.724-0.930) (

conclusionMachine learning algorithms improve the accuracy of risk stratification in patients with COVID-19. Using detection algorithms derived from these techniques can enhance the identification of critically ill patients.

Indexed as

COVID-19high sensitivity C-reactive proteinmachine learningprediction modelprocalcitonin

Identifiers

PMID34349576
PMCPMC8328384

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