ReviewDrug, healthcare and patient safety2021
Rational Drug Use Evaluation Based on World Health Organization Core Drug Use Indicators in Ethiopia: A Systematic Review.
Review in Drug, healthcare and patient safety, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Pooled it
- Pooled it
- The Pattern of Medicine Use in Ethiopia Using the WHO Core Drug Use Indicators.BioMed research international · 2021Pooled it
- A Systematic Review on Evaluation of WHO Core Prescribing Indicators Across Healthcare Facilities in Low Resource Asian Setting: A Case of Nepal.Inquiry : a journal of medical care organization, provision and financingPooled it
- Magnitude of intestinal parasites, enteric bacterial infections, antimicrobial susceptibility, and associated factors among street food vendors in Bule Hora town, south Ethiopia.Parasite epidemiology and control · 2026Article
- Problems associated with the ATC system of drug classification.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Clinical pharmacists and drug-related problem management in a South African hospital.Health SA = SA Gesondheid · 2026Article
- Drug use patterns at a Kenyan referral hospital: A cross-sectional study using WHO core indicators.PloS one · 2026Article
- Irrational medicine use and its associated factors in conflict-affected areas in Mali: a cross-sectional study.Global health action · 2025Article
- Assessment of drug utilization evaluation and post-dispensing knowledge of ophthalmic medications: an explanatory sequential mixed-methods study at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia.BMC health services research · 2025Article
- Design and Evaluation of ACAFiB-APP, a clinical decision support system for anticoagulant considerations in patients with atrial fibrillation.BMC cardiovascular disorders · 2025Article
- Drug prescription patterns and compliance with WHO and beers criteria in older patients.BMC geriatrics · 2025Article
- Adherence to WHO/INRUD prescription indicators in public hospitals: evidence from the Ashanti Region, Ghana.Therapeutic advances in drug safety · 2025Article
- Minimising inhaled corticosteroids for COPD.African journal of primary health care & family medicine · 2024Article
- Evaluation of a short-structured learner-centric training program on rational drug prescribing for medical interns: A quasi-experimental study.Journal of family medicine and primary care · 2024Article
- Assessment of knowledge and perception of prescribers towards rational medicine use in the Ashanti Region of Ghana.PloS one · 2024Article
- Drug Use Evaluation of Tenofovir/Lamivudine/Dolutegravir (TLD) Fixed-Dose Combination for Initiation and Transition Among HIV-Infected Individuals Attending Lumame Primary Hospital, North West Ethiopia.Integrated pharmacy research & practice · 2024Article
- Evaluation of Rational Medicines Use Based on World Health Organization Core Indicators: A Cross-Sectional Study in Five Health Districts in Mauritania.Integrated pharmacy research & practice · 2024Article
- Epidemiological study of antimicrobial-resistant bacteria in healthy free-ranging bantengs (Veterinary world · 2023Article
- Drug information-seeking behaviour among Jordanian physicians: a cross-sectional study.Frontiers in pharmacology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRational use of medicines plays a vital role in avoiding preventable adverse drug effects, maximizing therapeutic outcomes with promoting patient adherence, and minimizing the cost of drug therapy. Irrational use of drugs is often observed in countries with weak health care systems. No review has been done that systematically expresses rational drug use practice based on the three WHO core drug use indicators in Ethiopia. Thus, this study was aimed to review systematically the prescribing, health-facility, and patient-care indicators based on WHO core drug use indicators in Ethiopia.
methodsA systematic article search was conducted in different electronic databases including PubMed/ MEDLINE, the Cochrane Library, EMBASE, Web of Science, POPLINE, the Global Health, and Google scholar. Quality assessment was conducted using Newcastle-Ottawa quality assessment scale. Studies were synthesized and grouped in to prescribing, patient care and health facility indicators.
resultsFrom a total of 6239 articles, 21 studies were found suitable for the review. The highest average number of drugs per encounter was 2.5 while the lowest was 0.98. The percentage of generic drug use was ranged from 70.5% to 100%. The highest percentage of encounters with an antibiotic was 85%. The lowest percentage of drugs prescribed from essential drugs list was 81.4%. The highest percentage of drugs actually dispensed and adequately labeled was 96.16% and 96.25%, respectively.
conclusionThis study showed that the practice of rational drug use varied across region of the country. The average number of drugs per prescription, percentage of drugs encounter with antibiotics, drugs prescribed by their generic name, average consultation time, average dispensing time, percentage of drugs adequately labeled, and availability of essential drugs showed deviation from the standard recommended by WHO. Thus, provision of regular training for prescribers and pharmacists, and ensuring the availability of essential drugs should be encouraged.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.