Evidence map›Paper›PMID 34349495›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2021

Challenges in Diabetic Macular Edema Management: An Expert Consensus Report.

Patricia Udaondo, Alfredo Adan, Luis Arias-Barquet, Francisco J Ascaso, Francisco Cabrera-López, Verónica Castro-Navarro, Juan Donate-López, Alfredo García-Layana, Francisco Javier Lavid, Mariano Rodríguez-Maqueda and 1 more

Open access · goldAbstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Nonadherence to anti-VEGF intravitreal injections in patients with diabetic macular edema : The names of the authors.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
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  6. ESASO classification relevance in the diagnosis and evolution in diabetic macular edema patients after dexamethasone implant treatment.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 10 institutions in 1 country.

Patricia UdaondoDepartment of Ophthalmology, Hospital Universitario y Politecnico la FE, Valencia, Spain.ORCID 0000-0002-5241-0066
Alfredo AdanDepartment of Ophthalmology, Hospital Clinic Barcelona, Barcelona, Spain.ORCID 0000-0001-8923-2200
Luis Arias-BarquetDepartment of Ophthalmology, University Complex Bellvitge, Barcelona, Spain.ORCID 0000-0001-7041-5576
Francisco J AscasoDepartment of Ophthalmology, Hospital Universitario Lozano Blesa, Zaragoza, Spain.
Francisco Cabrera-LópezDepartment of Ophthalmology, Hospital Universitario Insular, Las Palmas de Gran Canaria, Spain.ORCID 0000-0002-5074-5102
Verónica Castro-NavarroDepartment of Ophthalmology, Hospital General Universitario, Valencia, Spain.
Juan Donate-LópezDepartment of Ophthalmology, Hospital Clínico San Carlos, Madrid, Spain.
Alfredo García-LayanaDepartment of Ophthalmology, Clínica Universitaria de Navarra, Pamplona, Spain.
Francisco Javier LavidDepartment of Ophthalmology, Hospital Punta Europa, Algeciras, Cádiz, Spain.ORCID 0000-0003-4229-8565
Mariano Rodríguez-MaquedaDepartment of Ophthalmology, Hospital Virgen del Rocío, Sevilla, Spain.
José María Ruiz-MorenoDepartment of Ophthalmology, Hospital Puerta de Hierro, Majadahonda, Madrid, Spain.
Bellvitge University Hospital · ESClinica Universidad de Navarra · ESHospital Clínic de Barcelona · ESHospital Clínico San Carlos · ESHospital Clínico Universitario Lozano Blesa · ESHospital General Universitario De Valencia · ESHospital Universitari i Politècnic La Fe · ESHospital Universitario Insular de Gran Canaria · ESHospital Universitario Puerta de Hierro Majadahonda · ESHospital Universitario Virgen del Rocío · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis paper aimed to present daily-practice recommendations for the management of diabetic macular edema (DME) patients based on available scientific evidence and the clinical experience of the consensus panel.

methodsA group of Spanish retina experts agreed to discuss different aspects related with the clinical management of DME patients.

resultsPanel was mainly focused on therapeutic objectives in DME management; definition terms; and role of biomarkers as prognostic and predictive factors to intravitreal treatment response. The panel recommends to start DME treatment as soon as possible in those eyes with a visual acuity less than 20/25 (always according to the retina unit capacity). Naïve patient was defined, in a strict manner, as a patient who, up to that moment, had never received any treatment. A refractory DME patient may be defined as the one who did not achieve a complete resolution of the disease, regardless of the treatment administered. Different optical coherence tomography biomarkers, such as disorganization of the retinal inner layers, hyperreflective dots, and cysts, have been identified as prognostic factors.

conclusionThis document has sought to lay down a set of recommendations and to identify key issues that may be useful for the daily management of DME patients.

Indexed as

biomarkersconsensusdiabetesdiabetic macular edemainflammationoptical coherence tomography

Identifiers

PMID34349495
PMCPMC8327476
OpenAlexW3183509501

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.