Evidence map›Paper›PMID 34349379›Full record

ArticleJournal of anaesthesiology, clinical pharmacology

Comparative evaluation of analgesic efficacy of buprenorphine transdermal patch and fentanyl patch in management of postoperative pain after arthroscopic lower limb surgery: A randomized controlled trial.

Hariom Khandelwal, Anoop Negi, Nishith Govil, Ashutosh Singh, Kumar Parag, Bharat Bhushan Bhardwaj

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Journal of anaesthesiology, clinical pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06949826 (A Single-institution, Parallel, Double-blinded, Randomized Study Assessing the Safety and Efficacy of Transdermal Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06949826 phase4recruitingnot on this map

A Single-institution, Parallel, Double-blinded, Randomized Study Assessing the Safety and Efficacy of Transdermal Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery

TypeinterventionalSponsorJenna-Leigh WilsonRan2025 to 2027Enrolled100ConditionsPain, Postoperative, Ankle Fracture Surgery, Opioid Use Disorder, Opioid DependenceArmsBuprenorphine Transdermal System, Placebo Patch
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Transdermal opioids for acute postoperative pain: A road less travelled!Journal of anaesthesiology, clinical pharmacology
    Article
  4. Review
  5. Transdermal opioids for acute postoperative pain: A road less travelled!Journal of anaesthesiology, clinical pharmacology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution.

Hariom KhandelwalDepartment of Anesthesia, SGRRIM and HS Dehradun, Rishikesh, Uttarakhand, India.
Anoop NegiDepartment of Anesthesia, SGRRIM and HS Dehradun, Rishikesh, Uttarakhand, India.
Nishith GovilDepartment of Anaesthesiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.
Ashutosh SinghDepartment of Anesthesia, SGRRIM and HS Dehradun, Rishikesh, Uttarakhand, India.
Kumar ParagDepartment of Cardiac Anesthesia, SGRRIM and HS Dehradun, Rishikesh, Uttarakhand, India.
Bharat Bhushan BhardwajDepartment of Emergency Medicine, All India Institute of Medical Sciences Rishikesh, Uttarakhand, India.
All India Institute of Medical Sciences Rishikesh

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsTransdermal opioids are newer modality in use for the control of postoperative pain, because of its noninvasiveness, longer duration of action, sustained blood levels, and with minimal side effects. The study was aimed to evaluate the efficacy of analgesia of buprenorphine patch 10, 20 μg·h MATERIALS AND

methodsIt was a randomized, double-blinded, prospective study in which adult patients undergoing lower limb arthroscopic surgery were randomly segregated into three groups. In Group 1 (fentanyl patch 25 μg·h

resultsOut of 175 screened patients, 150 patients were finally analyzed. Baseline characteristics were the same among all the three groups. Median NRS score was lowest in Group 3 [

conclusionsIn arthroscopic lower limb surgery, buprenorphine patch (20 μg·h

Indexed as

Acute painbuprenorphine patchfentanyl patchpain managementpostoperative analgesia

Identifiers

PMID34349379
PMCPMC8289665
OpenAlexW3183926591

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.