ReviewJournal of anaesthesiology, clinical pharmacology
Sugammadex and anaphylaxis: An analysis of 33 published cases.
Review in Journal of anaesthesiology, clinical pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- Article
- Neuromuscular Blocking Agents in Anesthesia: A Narrative Review of Contemporary Challenges and Reversal Approaches.Journal of clinical medicine · 2026Review
- Kounis Syndrome in Cardiac Surgery: Pathophysiology, Antimicrobial Triggers, and Perioperative Recognition and Management.Medical sciences (Basel, Switzerland) · 2026Review
- In-depth exploration of sugammadex and novel neuromuscular blockade antagonists: a narrative review.Frontiers in pharmacology · 2026Review
- Severe Suspected Anaphylaxis due to Sugammadex in a Healthy Patient Undergoing Endoscopic Sinus Surgery: A Case Report.Case reports in anesthesiology · 2026Article
- Article
- Sugammadex and emergence-related respiratory adverse events in pediatric tonsillectomy: a randomized controlled trial.Anesthesia and pain medicine · 2025Article
- Anesthesia information system-assisted detection and effective management of sugammadex-induced anaphylaxis: a case report.BMC anesthesiology · 2025Article
- Article
- Rocuronium for Treatment of Sugammadex Anaphylaxis: A Case Report.Case reports in anesthesiology · 2025Article
- Review
- Sugammadex for our little ones: a brief narrative review.Anesthesia and pain medicine · 2024Review
- Allergic Reactions to Sugammadex: A Case Series and Review of the Literature.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2023Article
- Successful management of rocuronium-induced anaphylaxis with sugammadex: A case report.The Journal of international medical research · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, the published sugammadex-induced anaphylaxis reports were reviewed to determine similarities in their presentation during anesthesia. PubMed was searched for sugammadex-induced anaphylaxis without time limitation. Reports were evaluated if they were in English and met the criteria of anaphylaxis determined by the World Allergy Organization. Two independent reviewers extracted and assessed the data using predesigned data collection forms. In total, 23 suitable articles were found and 33 sugammadex-induced anaphylaxis cases were included in the study. The mean age was 43.09 years (from 3-89 years) and 17 (51.5%) of the patients were female. Considering all reported cases, the average onset time of anaphylaxis was 3.08 min, with a median of 3 min (range 1-8 min). The most common signs and symptoms were hypotension, tachycardia, erythema, and desaturation. Of the 20 patients who underwent confirmatory skin testing, 15 had a positive skin reaction for sugammadex. Epinephrine was not given when indicated in about 25% of cases. Sugammadex-induced anaphylaxis onset time was less than 5 min in 92.3% of all the reported cases. Rapid diagnosis and early recognition of signs and symptoms of anaphylaxis are essential for a favorable prognosis. Treatment needs to be started as soon as possible to ensure the best outcome for the patient.
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Registered trials
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