Evidence map›Paper›PMID 34349323›Full record

ArticleAnesthesia, essays and researches

Premedication for Induced Hypotension in Functional Endoscopic Sinus Surgeries: Intravenous Dexmedetomidine Infusion vs Oral Metoprolol vs Placebo: A Comparative Study.

Lakshmi Mahajan, Arvinder Pal Singh, Sunil Chawla, Sukhman Gill

Open access · hybridAbstract read
In one paragraph

Article in Anesthesia, essays and researches. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Does preoperative administration of hypotensive agents affect the quality of the surgical field during endoscopic sinus surgery? A triple-blind randomized controlled trial.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Trial
  2. The Effect of Premedication with Metoprolol on the Surgical Field during Endoscopic Stapedectomy.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lakshmi MahajanDepartment of Anaesthesiology and Critical Care, SGRD Medical College and Hospital, Amritsar, Punjab, India.
Arvinder Pal SinghDepartment of Anaesthesiology and Critical Care, SGRD Medical College and Hospital, Amritsar, Punjab, India.
Sunil ChawlaDepartment of Anaesthesiology and Critical Care, SGRD Medical College and Hospital, Amritsar, Punjab, India.
Sukhman GillDepartment of Anaesthesiology and Critical Care, SGRD Medical College and Hospital, Amritsar, Punjab, India.
Government Medical College, Amritsar · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundControlled hypotension has been used to reduce bleeding and the need for blood transfusions and provide a satisfactory bloodless surgical field. In this double-blind, randomized controlled trial, we are comparing intravenous (i.v.) dexmedetomidine infusion and oral metoprolol as a premedication for controlled hypotension in functional endoscopic sinus surgery (FESS) for evaluating surgical field visibility. SUBJECTS AND

methodsA total of 90 patients undergoing FESS were randomly divided into three groups of 30 each. Group A received intraoperative i.v. infusion of dexmedetomidine (loading 1 μg.kg

resultsThe three groups were statistically comparable in demographics. Quality of surgical field was better in Group A compared to other two groups. Total blood loss was also less in Group A. The incidence of adverse reactions was more in Group A.

conclusionDexmedetomidine provides a better surgical field compared to oral metoprolol in FESS along with the desired hemodynamics with lesser blood loss and better outcome.

Indexed as

Controlled hypotensionfunctional endoscopic sinus surgeryintravenous dexmedetomidinemean arterial blood pressureoral metoprololsevofluranesurgical field visibility

Identifiers

PMID34349323
PMCPMC8294423
OpenAlexW3170492272

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.