ArticleAnesthesia, essays and researches
A Comparative Study of Periarticular Infiltration with Dexmedetomidine versus Ketorolac as an Additive to Ropivacaine after Total Knee Arthroplasty: A Prospective, Randomized Double-Blind Study.
Article in Anesthesia, essays and researches. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- Comparative Study of Effect of Periarticular Fentanyl and Dexmedetomidine Injection for Pain Management in Total Knee Arthroplasty a Randomized Control Trial.Journal of orthopaedic case reports · 2026Article
- Local infiltration anesthesia with high dose ropivacaine and dexmedetomidine in major knee surgery is safe.Archives of orthopaedic and trauma surgery · 2025Article
- Periarticular infiltration used in total joint replacements: an update and review article.Journal of orthopaedic surgery and research · 2023Review
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeriarticular infiltration (PAI) analgesia has been found to be an effective analgesia modality after total knee arthroplasty (TKA). Dexmedetomidine has many beneficial effects on postoperative analgesia by different routes, but studies on PAI are lagging. AIMS AND
objectivesIn this study, we compared postoperative analgesia after PAI with dexmedetomidine versus ketorolac as an additive to ropivacaine after TKA. SETTING AND
designThis is a prospective, randomized, double-blind study conducted on 75 patients belonging to American Society of Anesthesiologists I to III, undergoing total knee arthroplasty, of either gender, belonging to American Society of Anesthesiologists I to III. MATERIALS AND
methodsAfter institutional ethics committee approval and written informed consent, patients were randomly allocated into three groups. Group C ( STATISTICAL ANALYSIS: The Statistical Package for the Social Sciences version 20 was used for statistical analysis. Analysis of variance has been used to find the significance of study parameters between the three groups of patients.
resultsPostoperative pain score was lesser in the ketorolac group (1.52 ± 0.71,
conclusionKetorolac was a better additive to ropivacaine than dexmedetomidine for postoperative analgesia after TKA.
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