ArticleNature2021
Microbes exploit death-induced nutrient release by gut epithelial cells.
Open access · greenAbstract read
In one paragraph
Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
12.5field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 107 citations in OpenAlex.
- Muribaculum as a microbial contributor of rifaximin-induced mucosal protection during chemotherapy.Gut microbes · 2026Article
- Crosstalk between the microbiota and intestinal γδ T cell compartments in health and IBD.Gut microbes · 2026Review
- Pathogenicity and vaccine protection of circulating pertactin- and filamentous hemagglutinin-deficientEmerging microbes & infections · 2026Article
- Bifidobacterium breve inhibits colorectal cancer via extracellular vesicles containing formate acetyltransferase.Journal of nanobiotechnology · 2026Article
- Human DNA levels in feces reflect gut inflammation and associate with presence of gut species in IBD patients across the age spectrum.Microbiome · 2026Article
- Shaping death: how the microbiome regulates tumour cell demise and therapy response.Cancer metastasis reviews · 2026Review
- Dead but not gone: the interplay between the programmed cell death process and surrounding bacteria.Infection and immunity · 2026Review
- Exploring microorganism-host interactions: Emerging organoid models and analytical approaches.mLife · 2026Review
- ScRNA-seq reveals dynamic macrophage heterogeneity in chronic liver disease progression and prognostic biomarkersFrontiers in immunology · 2026Article
- Infection strategies ofGut microbes reports · 2026Review
- Myokine-mediated mechanisms of immune checkpoint inhibitors-associated colorectal injury and repair in rectal cancer.Frontiers in immunology · 2026Review
- The interplay of estrogen, gut microbiome, and bone immunity in osteoporosis.Cell communication and signaling : CCS · 2025Review
- Metabolic plasticity enables Clostridioides difficile growth in coculture with neutrophils and other mammalian cells.Anaerobe · 2025Article
- Effects of intergenerational transmission of small intestinal bacteria cultured from stunted Bangladeshi children with enteropathy.bioRxiv : the preprint server for biology · 2025Article
- Targeting pyroptosis in inflammatory bowel disease: A potentially effective therapeutic approach.World journal of gastroenterology · 2025Review
- Magnetite Micro/Nanorobots for Efficient Targeted Alleviation of Inflammatory Bowel Disease.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Metabolic ecology of microbiomes: Nutrient competition, host benefits, and community engineering.Cell host & microbe · 2025Review
- Caspase-1-licensed pyroptosis drives dsRNA-mediated necroptosis and dampens host defense against bacterial pneumonia.PLoS pathogens · 2025Article
- Article
- Mechanisms conferring multi-layered protection against intestinal Salmonella Typhimurium infection.FEMS microbiology reviews · 2025Review
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 5 institutions in 2 countries.
Christopher J AndersonVIB-UGent Center for Inflammation Research, Ghent, Belgium.ORCID http://orcid.org/0000-0003-2600-0968
Christopher B Medina *Center for Cell Clearance, Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, VA, USA.
Brady J Barron *Center for Cell Clearance, Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, VA, USA.ORCID http://orcid.org/0000-0002-6938-3789
Laura KarvelyteVIB-UGent Center for Inflammation Research, Ghent, Belgium.
Tania Løve AaesVIB-UGent Center for Inflammation Research, Ghent, Belgium.ORCID http://orcid.org/0000-0001-6813-8629
Irina LambertzVIB-UGent Center for Inflammation Research, Ghent, Belgium.
Justin S A PerryImmunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0003-4063-6524
Parul MehrotraVIB-UGent Center for Inflammation Research, Ghent, Belgium.
Amanda GonçalvesVIB-UGent Center for Inflammation Research, Ghent, Belgium.
Kelly LemeireVIB-UGent Center for Inflammation Research, Ghent, Belgium.
Gillian BlanckeVIB-UGent Center for Inflammation Research, Ghent, Belgium.
Vanessa AndriesVIB-UGent Center for Inflammation Research, Ghent, Belgium.
Farzaneh GhazaviVIB-UGent Center for Inflammation Research, Ghent, Belgium.
Arne MartensVIB-UGent Center for Inflammation Research, Ghent, Belgium.ORCID http://orcid.org/0000-0002-9816-2512
Geert van LooVIB-UGent Center for Inflammation Research, Ghent, Belgium.ORCID http://orcid.org/0000-0002-8427-4775
Lars VereeckeVIB-UGent Center for Inflammation Research, Ghent, Belgium.
Peter VandenabeeleVIB-UGent Center for Inflammation Research, Ghent, Belgium.
Kodi S RavichandranVIB-UGent Center for Inflammation Research, Ghent, Belgium. kodi.ravichandran@irc.vib-ugent.be.ORCID http://orcid.org/0000-0001-9049-1410
Ghent University · BEGhent University Hospital · BEUniversity of Virginia · USMemorial Sloan Kettering Cancer Center · USVIB-UGent Center for Inflammation Research · BE
Funding
Role of Pannexins in Vascular Smooth Muscle CellsP01HL120840 · NHLBI · UNIVERSITY OF VIRGINIA · PI BAYLISS, DOUGLAS A., RAVICHANDRAN, KODI S · 2014 to 2023
$24.0MTRAINING IN THE PHARMACOLOGICAL SCIENCEST32GM007055 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI LYNCH, KEVIN R. · 1985 to 2022
$7.2MMechanisms regulating apoptotic cell clearance in health and diseaseR35GM122542 · NIGMS · WASHINGTON UNIVERSITY · PI RAVICHANDRAN, KODI S · 2017 to 2021
$2.3MEuropean Research CouncilNHLBI NIH HHS P01 HL120840NIGMS NIH HHS R35 GM122542NIGMS NIH HHS T32 GM007055
Abstract
Regulated cell death is an integral part of life, and has broad effects on organism development and homeostasis
Indexed as
ApoptosisAcetyltransferasesAnimalsCaspase 3Caspase 7Cell LineDisease Models, AnimalEnterobacteriaceaeEpithelial CellsFemaleFoodborne DiseasesGerm-Free LifeHost-Pathogen InteractionsInflammationIntestinesMaleAcetyltransferasesCaspase 3Caspase 7formate C-acetyltransferaseTnfaip3 protein, mouseTumor Necrosis Factor-alphaTumor Necrosis Factor alpha-Induced Protein 3
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.