Evidence map›Paper›PMID 34349260›Full record

ArticleNature2021

The structural basis of odorant recognition in insect olfactory receptors.

Josefina Del Mármol, Mackenzie A Yedlin, Vanessa Ruta

Open access · hybridAbstract read
In one paragraph

Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 159 papers.

0numbers the graph read from it
0cells of the map it votes in
159citing papers in PubMed
22.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

159 citing papers in PubMed, 288 citations in OpenAlex.

  1. PharmaGNN: a model for odor prediction based on graph neural networks.Journal of the science of food and agriculture · 2026
    Article
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  6. Integrated Ultrastructural and Transcriptomic Analysis of the Proboscis inAnimals : an open access journal from MDPI · 2026
    Article
  7. Review
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  16. Microbial Odorant Detection Guides Drosophila Parasitoids Seeking Hosts in Fermenting Fruits.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  17. Scent and adhesion drive insect dispersal of environmental yeast.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  18. Article
  19. Article
  20. Article

99 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Josefina Del MármolLaboratory of Neurophysiology and Behavior, The Rockefeller University, New York, NY, USA.
Mackenzie A YedlinLaboratory of Neurophysiology and Behavior, The Rockefeller University, New York, NY, USA.ORCID http://orcid.org/0000-0003-4085-9509
Vanessa RutaLaboratory of Neurophysiology and Behavior, The Rockefeller University, New York, NY, USA. ruta@rockefeller.edu.ORCID http://orcid.org/0000-0002-4963-2768
Rockefeller University · US

Funding

Molecular Mechanisms Underlying Insect Odorant Receptor Function and ModulationR01AI103171 · NIAID · ROCKEFELLER UNIVERSITY · PI RUTA, VANESSA · 2014 to 2024
$4.5M
Elucidating the structural determinants of odor specificity in insect olfactory receptorsK99DC019401 · NIDCD · ROCKEFELLER UNIVERSITY · PI DEL MARMOL, JOSEFINA INÉS · 2021 to 2022
$138k
NIAID NIH HHS R01 AI103171NIDCD NIH HHS K99 DC019401
6 · The paper itself

Abstract

Olfactory systems must detect and discriminate amongst an enormous variety of odorants

Indexed as

Ion Channel GatingAnimalsBinding SitesCell LineDEETEugenolInsectaInsect ProteinsIon ChannelsModels, MolecularMutationOdorantsProtein BindingProtein Structure, QuaternaryReceptors, OdorantSubstrate SpecificityDEETEugenolInsect ProteinsIon ChannelsReceptors, Odorant

Identifiers

PMID34349260
PMCPMC8410599
OpenAlexW3189459060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.